نتایج جستجو برای: tissue inhibitor matrix metalloproteinase 1
تعداد نتایج: 3736052 فیلتر نتایج به سال:
objective: diabetes plays an important role in the progression of tissue damage. influencing factors of the cellular matrix can lead to changes in the structure and function of tissues or their failure. herbal consumption can be effective in reducing tissue failure. the aim of the this study is to research the effect portulaca oleracea seeds on the levels of matrix metalloproteinase 2, 9 and ti...
breast cancer patients are susceptible to infections such as candidiasis. due to the importance and the role of matrix metalloproteinases (mmp) in breast cancer progression and its correlation with tumor metastasis, we analyzed the serum level of mmps -2, -3, -9 and tissue inhibitor of matrix metalloproteinase-1 (timp-1) in breast cancer bearing mice in the presence of systemic candida ...
angiotensin ii, the main component of the renin-angiotensin system, is associated with cardiovascular diseases such as hypertension, vascular remodeling and inflammation. remodeling process results from dysregulation of matrix metalloproteinases (mmps) and their tissue inhibitors (timps). mmps are considered as important target genes for angiotensin ii. the aim of this study was to determine th...
Matrix metalloproteinase-14 is required for degradation of fibrillar collagen by mesenchymal cells. Here we show that keratinocytes use an alternative plasminogen and matrix metalloproteinase-13-dependent pathway for dissolution of collagen fibrils. Primary keratinocytes displayed an absolute requirement for serum to dissolve collagen. Dissolution of collagen was abolished in plasminogen-deplet...
background: considering the role of matrix metalloproteinase-3 (mmp-3) and tissue inhibitor of matrix metalloproteinase-1 (timp-1) in the pathogenesis of periodontitis, the present study is to estimate the levels of mmp-3 and timp-1 in gingival crevicular fluid (gcf) in periodontal health, disease and to evaluate the effect of periodontal therapy on mmp-3 and timp-1 concentrations in gcf. mater...
OBJECTIVE Matrix metalloproteinase-9 is considered to play a pivotal role in aneurismal formation. We showed that gingival fibroblasts (GF) in vitro reduced matrix metalloproteinase-9 activity via increased secretion of tissue inhibitor of metalloproteinase 1. We aimed to evaluate in vivo the efficacy of GF transplantation to reduce aneurism development in a rabbit model. METHODS AND RESULTS ...
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