Tinospora cordifolia (Guduchi) is an important herb in folk and ayurvedic systems of medicine. This paper presents a critical review on chemical and biological properties of Tinospora cordifolia. Tinospora cordifolia contain various chemical constituents belonging to different classes such as alkaloids, diterpenoid lactones, glycosides and steroids. The most important biological properties repo...

Background. Tinospora cordifolia, an Indian medicinal plant, has been reported to have beneficial effects on disorders like peptic ulcer, hepatobiliary disorders, rheumatism, infectious diseases etc. It enhances cognition in normal rats and successfully overcomes cyclosporine induced memory deficit. Methods. Thirty healthy volunteers of age 18-30 years received Tinospora cordifolia (500 mg of p...

Seed oils of Passiflora edulis, Jatropa curucas, Tinospora cordifolia, Sesbania grandiflora and Sapindus laurifolia were investigated for their antihelmintic property against Pheritima pasthuma. Three concentrations (10, 50 and 100 mg/ml) of each oil were studied in the bioassay, which involved the determination of time of paralysis and time of death of the worm. Sesbania grandiflora showed the...

The methanol leaf extracts of Acacia nilotica, Sida cordifolia, Tinospora cordifolia, Withania somnifer and Ziziphus mauritiana showed significant antibacterial activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Staphylococcus aureus and Xanthomonas axonopodis pv. malvacearum and antifungal activity against Aspergillus flavus, Dreschlera turcica and Fusarium verticil...

The methanol leaf extracts of Acacia nilotica, Sida cordifolia, Tinospora cordifolia, Withania somnifer and Ziziphus mauritiana are ethnomedicinally important showed significant antibacterial and activity against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Staphylococcus aureus and Xanthomonas axonopodis pv. malvacearum and antifungal activity against Aspergillus flavus, Dresc...

The purpose of present study was to evaluate the testes and epididymides mediated reversible contraceptive efficacy of ethanol extract of Tinospora cordifolia stem at the dose level of 400mg/kg. b.wt./rat/day. Oral treatment of 60 days caused significant reduction in number of spermatozoa in cauda epididymides as well as in testis with a decreased in the motility of sperm collected from cauda e...

The importance of Tinospora cordifolia stem extract was investigated for its possible curative effect in male wistar rats against the cisplatin induced nephrotoxicity. Oral administration of plant extract cured the cisplatin induced kidney damage. There was an increase in serum creatinine, blood urea nitrogen and alkaline phosphatase in rats treated with Cisplatin (5mg/kg body weight, i.p). Adm...

The antibacterial activity of the aqueous, ethanol and chloroform extracts from the stems of Tinospora cordifolia  was studied using disc diffusion method against Escherichia coil, Proteus vulgaris, Enterobacter faecalis, Salmonella typhi (Gram-negative), Staphylococcus aureus and Serratia marcesenses (Gram-positive). Results suggest that the ethanolic extract has significant antibacterial acti...

Tinospora cordifolia is commonly known as Gulancha in Bangladesh is belongs to Menispermaceae family and it is also available all over the world. It is widely used as a unique ingredient of various natural medicine and traditionally use for numerous aliment like fever, vomiting, diabetes, jaundice, anaemia, polyuria and skin diseases etc. It has hypoglycemic, antipyretic, anti-allergic, Antineo...

Tinospora cordifolia is a deciduous climbing shrub described as ‘the one who protects the body against diseases’. Potential medicinal properties reported by scientific research include anti-diabetic, anti-pyretic, antispasmodic, anti-inflammatory, anti-arthritic, antioxidant, antiallergic, anti-stress, hepato-protective, anti-malarial, immunemodulatory and anti-neoplastic activity. In our study...