background: imatinib mesylate is the first generation of tyrosine kinase inhibitors (tki) and highly effective in the treatment of chronic myeloid leukemia (cml). we aimed to evaluate thyroid function at baseline and at 1, 3, 6 and 12 months after initiation of imatinib mesylate therapy in 20 newly diagnosed bcr-abl positive cml patients. methods: this study was done during 2013-2014, 20 new ca...

objective to determine the changes in thyroid function tests in children who underwent antiepileptic therapy in shahid beheshti hospital, kashan, in 2008. materials & methods this analytical-observational study was carried out in a cohort fashion without an external control group (self controlled) on 45 children with new onset epilepsy who had not been previously treated with antiepileptic medi...

background and objective: hypothyroidism is a known consequence of the external beam radiotherapy to the neck encompassing the thyroid gland for over 40 years. the aim of this study was to find out the incidence of hypothyroidism in patients with head and neck cancer treated with radiotherapy, when radiation portals included whole of the thyroid gland. materials and methods: this prospective no...

introduction: imatinib, a tyrosine kinase inhibitor which resulted in much improvement in the treatment of chronic myelogenous leukemia (cml), may adversely affect thyroid gland function. to date, assessment of thyroid function during imatinib therapy has limited to retrospective studies. the aim of this study was to evaluate the effects of imatinib on thyroid function in a prospective manner. ...

purpose: to evaluate the prevalence of clinical and subclinical thyroid disorders using thyroid function tests in patients with single and multiple chalazia. methods: a complete ophthalmologic examination and thyroid function tests including thyroid stimulating hormone (tsh), thyroxine (t4) and triiodothyronine (t3) were performed in 60 patients with single chalazia and 50 patients with multipl...

Background: Vitiligo is a pigmentary disorder of the skin, which has been reported in association with thyroid disorders. Objective: The aim of this study was to assess thyroid disorders in vitiligo patients. Patients and Methods: In this case-control study, thyroid function tests were evaluated in seventy patients with vitiligo and compared with a control group. Results: Nine of seventy patien...

atrial fibrillation or osteoporosis and makes the illogical extrapolation that a patient given a dose of thyroxine that suppresses or brings the serum thyroxine concentration to higher than the reference range is receiving too much replacement. It is excusable for doctors to believe that if the serum thyroxine concentration is higher than the so-called normal range that the dose of thyroxine sh...