نتایج جستجو برای: thymidine
تعداد نتایج: 13317 فیلتر نتایج به سال:
Background: Thymidine phosphorylase (TP) catalyses the conversion of thymidine into thymine. Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disease which is caused by mutations in the nuclear gene encoding TP, bringing about severe impairment of TP-enzyme specific activity and accumulation of thymidine in plasma. The clinical manifestations of MNGIE are ...
the effect of dietary sucrose on dna formation in rat liver and kidney compared with that of starch was studied. male, weanling rats were fed for 6 and 14 days on diets containing 68% 'sucrose or 68% starch, and liver and kidneys were examined for 1ilie amount and rate of formation of dna; and also for content of fat, protein, and moisture. food intake and weight gain were estimated. sucrose fe...
Objective: Zerumbone (ZER) is a well-known natural compound that has been reported to have anti-cancer effect. Thus, this study investigated the ZER potential inhibit Thymidine Phosphorylase (TP) and ability trigger Reactive oxygen species (ROS)-mediated cytotoxicity in non-small cell lung cancer, NCI-H460, line. Material Method: The antiangiogenic activity for was evaluated by using thymidine ...
Spectroscopic characterization of dipicolinic acid and its photoproducts as thymine photosensitizers
Dipicolinic acid (DPA), present in large amount bacterial spores, has been proposed to act as an endogenous photosensitizer spore photoproduct formation. The mechanism involves a triplet-triplet energy transfer from DPA thymine. However, up now, no spectroscopic studies have performed determine the interaction between compound and nucleobase, probably due its photolability aqueous solutions. He...
Background: Many in vitro studies suggested that choline incorporation into many types of tumors is related to cell proliferation. Whether in vivo choline incorporation is related also to cell proliferation or not was my question. Therefore, the aim of this pilot study was to investigate the relationship of in vivo [methyl- 14C]-choline incorporation and in vivo [methyl-3H]- thymidine incorpora...
herpes simplex virus type 1 establishes a latent infection in the peripheral nervous system following primary infection. during latent infection, virus genome exhibit limited transcription, with the hsv lats consistently detected in latency infected ganaglia. following ocular infection viral latency develops in the trigeminal ganglia. in this study pcr has been used for detection of hsv-1 nucli...
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