thrombolytic agents are among the medications that are used widely for the treatment of thromboembolic disorders and myocardial infarction (mi). despite the world-wide availability of newer specific agents, streptokinase (sk) is still the most frequently used medication from this class in iran. hence we conducted this study to review the adverse reactions to this medication which were reported ...

the important role of reperfusion therapies in the treatment of acute myocardial infarction is well documented. however, reperfusion therapies can initiate inflammatory response and may damage the myocardium. the purpose of current study was to compare the effects of percutaneous coronary intervention and thrombolytic therapy on inflammatory markers in the setting of st elevation myocardial inf...

Substantial progress has been made toward understanding the pathophysiological processes that lead to acute myocardial infarction. Research has shown that the mechanism of infarction is the rupture of an atherosclerotic plaque with a subsequent thrombogenic response from exposed subendothelial tissue, leading to additional or complete obstruction of the vessel. Myocardial cell death then procee...

CONTEXT A meta-analysis found that primary percutaneous transluminal coronary angioplasty (PTCA) was more effective than thrombolytic therapy in reducing mortality from acute myocardial infarction. However, fewer than 20% of U.S. hospitals have facilities to perform PTCA and many clinicians must choose between immediate thrombolytic therapy and delayed PTCA. COUNT The number of minutes of PTC...

Myocardial infarction, stroke, and pulmonary embolism are all deadly conditions associated with excessive thrombus formation. Standard treatment for these involves systemic delivery of thrombolytic agents to break up clots restore blood flow; however, this can impact the hemostatic balance in other parts vasculature, which lead bleeding. To avoid potential danger, targeted treatments that succe...

Thrombolysis and percutaneous transluminal angioplasty represent the cornerstone of the pharmacologic treatment of and the interventional approach to patients with myocardial infarction (MI). They are very effective. However, they are hampered by some critical limitations. Therefore, alternatives to standard thrombolytic therapy have been developed. Platelet glycoprotein (GP) IIb/IIIa blockade ...

PURPOSE OF REVIEW Numerous therapeutic options have been suggested for the treatment of central retinal artery occlusion (CRAO) such as ocular massage, anterior chamber paracentesis, physical exercise, and medication-induced reduction of intraocular pressure. Because of the lack of a proven effective treatment for CRAO, there has been a strong effort to develop alternative therapies. Recently, ...

background thrombolytic therapy in patients with sub-massive pulmonary embolism (smpte) needs further assessment. objectives the current study aimed to assess a potential benefit of thrombolytic and non-thrombolytic therapy in patients with smpte. patients and methods one hundred-nineteen patients were enrolled with smpte from 2006 to 2010 in the tertiary care center of rajaie medical and resea...

Acute revascularization is associated with improved outcomes in ischemic stroke patients. It is unclear which method of intra-arterial intervention, if any, is ideal. Promising approaches in acute stroke treatment are likely a combination of intravenous and endovascular revascularization efforts, combining early treatment initiation with direct clot manipulation and/or PTA/stenting. In this rev...