GThreonine dehydratase catalyzes the nonoxidative conversion of /Y-substituted amino acids to cr-keto acids. In this manuscript the nature of the nucleophiles which are eliminated is established, new substrates are reported, and inhibition by j&substituted alanines investigated. It is now shown that threonine dehydratase will catalyze the q/3 elimination of -OH, -Cl, and -F as HzO, and HX from ...

The recently discovered three dimensional or bulk topological insulators are expected to exhibit exotic quantum phenomena. It is believed that a trivial insulator can be twisted into a topological state by modulating the spin-orbit interaction or the crystal lattice via odd number of band inversions, driving the system through a topological quantum phase transition. By directly measuring the to...