نتایج جستجو برای: thiopental na

تعداد نتایج: 268200  

Background and Aim: Depression is a commomn common psychiatric disordersdisorder.. The Sever severe form of depression, that callled call.ed as . major depression , has many effects on the mental health of patient's patients. It may even lead to health including. suicidal attempt. Electro Convulsive Therapy (ECT) is still the most effective treatment for major depression. The purpose of this st...

Journal: :The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2008
Young-Yeob Ko Yong-Hoon Jeong Dong-Yoon Lim

The aim of the present study was to examine the effects of ketamine, a dissociative anesthetics, on secretion of catecholamines (CA) secretion evoked by cholinergic stimulation from the perfused model of the isolated rat adrenal gland, and to establish its mechanism of action, and to compare ketamine effect with that of thiopental sodium, which is one of intravenous barbiturate anesthetics. Ket...

Background: Intraosseous injection is a way to administration of drugs. Objective: The clinical comparison of intraosseous and intravenous injection of Thiopental-Na. Methods: First all birds (Twenty six healthy pigeons) were split out into two groups randomly. Group A received 20 mg kg-1 Thiopental-Na by intraosseous rou...

Journal: :Anesthesiology 2004
Laurence E Mather Colin C Duke Leigh A Ladd Susan E Copeland Gabrielle Gallagher Dennis H T Chang

BACKGROUND Previous evidence from laboratory animal studies indicates that R-thiopental has a greater margin of safety than either the more potent S-thiopental or the clinically used rac-thiopental. Although thiopental can cause cardiovascular depression from direct myocardial effects as well as indirect central nervous system and peripheral effects, no studies have yet determined whether its m...

Journal: :Stroke 1999
T Wang K M Raley-Susman J Wang G Chambers J E Cottrell I S Kass

BACKGROUND AND PURPOSE Thiopental has been shown to protect against cerebral ischemic damage; however, it has undesirable side effects. We have examined how thiopental alters histological, physiological, and biochemical changes during and after hypoxia. These experiments should enable the discovery of agents that share some of the beneficial effects of thiopental. METHODS We made intracellula...

Journal: :Anesthesia and analgesia 2005
Caroline Stabernack Yi Zhang James M Sonner Michael Laster Edmond I Eger

The spinal cord mediates most of the immobilizing action of inhaled anesthetics. In the present study we investigated whether spinal or supraspinal sites mediate the immobilizing action of thiopental in rats. Thiopental was administered IV, intrathecally (IT), intracerebroventricularly (ICV), or simultaneously IT and ICV. Only the IV infusion produced anesthesia, defined as immobility in respon...

Journal: :The American journal of physiology 1977
L D Horwitz

The cardiovascular effects of ketamine hydrochloride and thiopental sodium were studied in 11 dogs. During anesthesia, mean heart rate rose to 185 beats/min with ketamine and 147 beats/min with thiopental. Cardiac output was increased with ketamine but unchanged by thiopental. The maximum first derivative of the left ventricular pressure (dP/dt max) fell by 14% with thiopental but did not chang...

Journal: :Anesthesiology 2002
Joseph F Antognini Earl Carstens Richard Atherley

BACKGROUND Recent studies suggest that anesthetics such as isoflurane act in the spinal cord to suppress movement that occurs during noxious stimulation. The authors examined the effect of halothane and thiopental on suppression of noxious-evoked movement using a model of differential anesthetic delivery. They hypothesized that halothane and thiopental, similar to isoflurane, would suppress mov...

2015
Tae Kyong Kim Young-Jin Lim Jae-Woo Ju Jin Wook Kim Hee-Pyoung Park

OBJECTIVE The potassium disturbance associated with thiopental continuous infusion in neurosurgical patients is well known. However, the effect of propofol continuous infusion on serum potassium levels has not been investigated extensively. METHODS We reviewed the medical records of 60 consecutive patients who received coma therapy or deep sedation for intracranial pressure control using eith...

Journal: :Anesthesiology 2002
Robert Dickinson Sara L M de Sousa William R Lieb Nicholas P Franks

BACKGROUND There is conflicting evidence concerning the extent to which the intravenous general anesthetic thiopental acts by enhancing inhibitory gamma-aminobutyric acid-mediated (GABAergic) synaptic transmission or by inhibiting excitatory glutamatergic transmission. Yet there are remarkably few studies on the effects of thiopental on functional synapses. In addition, the degree of stereosele...

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