1,2,3-thiadiazoles were synthesized in parallel using a polymer sulfonyl hydrazide resin (PS-TsNHNH2) and employing a "catch and release" synthesis strategy. Resin capture of ketones synthesized from Weinreb amides and Grignard reagents afforded resin-bound sulfonylhydrazones. Cyclizative cleavage of supportbound sulfonylhydrazones with thionyl chloride afforded 1,2,3-thiadiazoles. Excess thion...

Key words synthesis - p-tolyl menthyl sulfinate enantiopure thionyl chloride sulfinic acid

It has been reported that sulfinamide anhydride is formed when anthranilic acid is treated with thionyl chloride under anhydrous conditions. Garin et al. reported that no sulfinamide anhydride was formed in the reaction of anthranilic acid with thionyl chloride. They reported that 2-(sulfinylamino) benzoyl chloride was formed, in accordance with an earlier observation, under the same reaction c...

the solvent free route for the synthesis of diaryl sulfoxides from arenes and thionyl chloride in the presence of lewis acids such as aluminum chloride and ferric chloride on silica gel are described.

The solvent free route for the synthesis of diaryl sulfoxides from arenes and thionyl chloride in the presence of Lewis acids such as aluminum chloride and ferric chloride on silica gel are described.

The specific conductivity of solutions of LiA1C14 dissolved in SOC12 was determined as a function of composition and temperature. An analytical expression from which the conductivity can be calculated is given as a function of the mole fraction of LiA1C14 and temperature in the ranges from 0 ~ to 0.37~ and from -20 ~ to +70~ respectively. LiAIC14-SOC14 mixtures are used commercially as electrol...

Reaction of thionyl chloride with 2-acetyl-1- benzenesulfonylpyrrole semicarbazone (6 c) gave 4 - (1- benzenesulfonyl-2 - pyrrolyl) - 1, 2, 3 -thiadiazole (lc). Selenium dioxide oxidation of 2-acetylpyrazine semicarbazone (10) in acetic acid afforded 4- (2-pyrazinyl) - 1, 2, 3- selenadiazole (4). Reaction of thionyl chloride with compound 10 gave 4- (2-pyrazinyl) - 1, 2, 3- thiadiazole (3)....

The X-ray structure of the title compound, formed at low conversion in reaction thiosalicylic acid with thionyl chloride, has been determined. chloride groups are oriented to permit an attractive non-bonding O…S interaction. Mechanisms suggested for formation this unexpected product. 1H and 13C NMR data also reported first time major product, 2-mercaptobenzoyl chloride.