نتایج جستجو برای: thalassemic

تعداد نتایج: 1036  

Journal: :Blood 1989
S L Schrier E Rachmilewitz N Mohandas

To define how excess unpaired alpha- and beta-globin chains in severe beta-thalassemia and severe alpha-thalassemia interacting with the membrane might alter cellular and membrane properties, we performed a series of biophysical and biochemical analyses on erythrocytes obtained from affected patients. Detailed analysis of cellular and membrane deformability characteristics showed that both form...

Journal: :Hepatitis monthly 2016
Bita Behnava Heidar Sharafi Maryam Keshvari Ali Pouryasin Leila Mehrnoush Shima Salimi Pegah Karimi Elizee Mehran Ghazimoghaddam Seyed Moayed Alavian

BACKGROUND Hepatitis C Virus (HCV) is the major cause of liver failure in thalassemic patients. In these patients, iron overload and their comorbidities make difficulties during Pegylated-Interferon (PEG-IFN) and Ribavirin (RBV) therapy. OBJECTIVES We aimed to assess the impact of polymorphisms near the IL28B gene on virological response in HCV - infected thalassemic patients, who were treate...

2013
Faiez N. Hattab

OBJECTIVES To provide a description of mesiodistal crown diameters (MD) and tooth-size discrepancy (TSD) of the permanent dentition in patients with thalassemia major (TM) and to compare the results with those of unaffected control group. STUDY DESIGN The sample consisted of 46 thalassemic patients, 25 males and 21 females aged 7.3 to 23.7 years (mean ± SD = 11.2 ± 3.9 years) and control grou...

Journal: :Bangladesh Medical Research Council bulletin 2010
Hassan Solhi Mojgan Hashemieh Mohammad Lorgard Dezfuli Nejad Hamid-Reza Khoddami Vishteh Maryam Rahmati Nejad

Rapid diagnosis of major beta thalassemia along with certain preventive measures is of utmost significance. The present study aims to compare the fingerprints in Major beta thalassemic patients (67) and in their parents (76 with minor thalassemia) with the normal fingerprints of control group (144). A forensic medical examiner determined fingerprint types of arch, loop, whorl and other types. L...

Journal: :Blood 1968
L M Slater W A Muir R I Weed

I NTRACELLULAR PRECIPITATES in ghosts prepared from red cells of patients with thalassemia major were described first by Hoffman1 in 1956. Such inclusions have been recognized in intact thalassemic erythrocytes by J osephson et al.,2 Fessas, ’ Nathan et al.46 and others. The present work was stimulated by observations of the difficulty involved in removing hemoglobin from thalassemic ghosts enc...

Journal: :Siriraj Medical Journal 2022

Objective: This study aimed to evaluate oral hygiene status, salivary fluoride concentration, and Streptococcus mutans Lactobacillus levels in saliva of thalassemic, hemophilic individuals without any other systemic disorders.Materials Methods: A total 162 (44 healthy individuals, 86 thalassemic 32 patients) were selected, randomly (n=30 each group), the patients allocated Group A: condition, B...

2011
Samin Alavi Zohreh Sharifi Ali Kord Valeshabad Kazem Nourbakhsh Bibi Shahin Shamsian Mohammad Taghi Arzanian Alieh Safarisharari Masoumeh Navidinia

BACKGROUND Although a marked proportion of thalassemic patients acquire Torque teno virus (TTV) through blood transfusion, its clinical importance is unclear. This study was designed to investigate the clinical importance of TTV infection in thalassemic patients with and without hepatitis C virus (HCV) co-infection in Iran. METHODS In this case-control study, 107 thalassemic patients on chron...

Journal: :Blood 1994
J Yuan E Rubin M Aljurf L Ma S L Schrier

beta-Thalassemic mice provide a useful model for studying the pathophysiology of human beta-thalassemia in that one can perform experiments that are difficult to perform in humans. The ease of access to beta-thalassemic mouse marrow provided the opportunity to explore the cause of the ineffective erythropoiesis that characterizes severe beta-thalassemia in mouse and man. We hypothesized that th...

2013
Doaa Mohammed Youssef Faten Fawzy Mohammad Ayman Ahmed Fathy Maha Aly Abdelbasset

Background. MRI has emerged for the noninvasive assessment of iron overload in various tissues. The aim of this paper is to evaluate hepatic and pancreatic iron overload by T2(∗) weighted gradient echo MRI in young beta-thalassemia major patients and to correlate it with glucose disturbance and postsplenectomy status. Subjects and Methods. 50 thalassemic patients, in addition to 15 healthy cont...

Journal: :Blood 1983
U Galili A Korkesh I Kahane E A Rachmilewitz

A modified antiglobulin test, based on the high affinity between the Fc portion of the red blood cell (RBC) bound IgG and the Fc receptor on the myeloid cell K-562, was utilized for demonstration of immunoglobulins (Ig) on thalassemic RBC. Ig was found on the RBC of 73 out of 80 patients with thalassemia. The immunoglobulins on the thalassemic RBC belonged to the IgG subclass and were autoreact...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید