background and aims: nowadays introduction of regular blood transfusion therapy has obviously improved the life expectancy of patients with thalassemia. however, these patients face with newer challenges which influence their quality of life (qol). in this study, the aim of this study was to measure qol among patients with β-thalassemia major (β-tm). methods: a cross-sectional study was done at...

Results The mean age was 27,5±16 (1-86) years. Our hospital mean follow-up period was 48,5±48 (1-352) months. 1343 patients (67,2%) had no comorbidities. 655 patients (32.8%) had comorbidities. Comorbidities were as follow: Appendectomy 30 (4,6%), cholecystectomy 20 (3,1%), acute rheumatic fever (2,4%), ankylosing spondylitis 155 (23,7%), juvenile idiopathic arthritis 31 (4,6%), rheumatoid arth...

Chronic diseases have been identified as predisposing factors in behavioral disorders and the prevalence of these disorders is known to be higher in patients than in control groups. Thalassemia too, plays an effective role in increasing the prevalence of behavioral disorders. In order to recognize the prevalence of behavioral disorders in thalassemic patients, a study was performed on 257 ...

chronic diseases have been identified as predisposing factors in behavioral disorders and the prevalence of these disorders is known to be higher in patients than in control groups. thalassemia too, plays an effective role in increasing the prevalence of behavioral disorders. in order to recognize the prevalence of behavioral disorders in thalassemic patients, a study was performed on 257 patie...

background: the majority of α-thalassemi mutations are deletions of one or both α-globin genes. since the iranian populaion is a mixture of different ethnic groups, frequency and distribution of globin mutations in various regions of the country need to be clarified. the aim of this study was to determine the common alpha globin gene deletions among individuals with hypochromic microcytic anemi...

Background and aims: Nowadays introduction of regular blood transfusion therapy has obviously improved the life expectancy of patients with thalassemia. However, these patients face with newer challenges which influence their quality of life (QoL). In this study, the aim of this study was to measure QoL among patients with β-thalassemia major (β-TM). Methods:</str...

Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...

thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. for β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...