fariba ghahramani department of epidemiology, school of public heath, shiraz university of medical sciences, shiraz, i mohammad amin rezaei department of laboratory sciences, school of paramedical, shiraz university of medical sciences, shi abdolreza afrasiabi shahid dastgheib hospital genetic center, shiraz university of medical sciences, shiraz, iran jamalledin nejad member of chancellor of health of shiraz university of medical sciences, shiraz, iran