Many species of Teucrium were used traditionally in treatment of inflammatory disorders. The present study aimed to assess the anti-inflammatory effect of methanolic extract of aerial parts of Teucrium oliverianum Ging. ex. Benth. (family, Lamiaceae). The extract was evaluated using the carrageenan-induced rat paw edema (Acute and sub-acute models), and turpentine oil–induced granuloma pouch bi...

Hepatoprotective activity of the ethyl acetate extract of Teucrium polium L. was investigated using rats with CCl4-induced liver damage. Specific biochemical parameters (glutathione peroxidase, superoxide dismutase, reduced glutathione and total antioxidative status) were estimated in blood and in liver homogenate. Lipid peroxidation in CCl4-intoxicated rats was evidenced by a marked increment ...

background: teucrium polium has been known as an important traditional medicinal plant and is used for different therapeutic purposes such as gastrointestinal disorders. therefore, the anti-spasmodic and antinociceptive activities of aqueous extract of teucrium polium w as examined. methods: anti-spasmodic effect of different concentrations (47-470 mg/l) of teucrium polium extract was assessed ...

BACKGROUND Diabetes has an adverse effect on spermatogenesis by rising oxidative stress. OBJECTIVE The aim of this study was to investigate the effect of Teucrium Polium extract administration on spermatogenesis and testicular structure in diabetic rats induced with Streptozotocin. MATERIALS AND METHODS 32 male Wistar rats were randomly divided into four groups (n=8/each): control group, di...

Background: Teucrium Polium and Prosopis Farcta have been traditionally employed in cancer treatment. In this study we evaluated the effects of methanolic extracts of these two plants in HT-29 cells. Methods: IC50s of extracts were obtained via MTT assay and the levels of ROS production, cell death, collapse of mitochondrial membrane potential and Sirt3 enzyme activity were determined. Results:...

We read with great interest the article by Hasanein and colleagues in the Medical Science Monitor Journal, entitled “Preventive effect of Teucrium polium on learning and memory deficits in diabetic rats” [1]. They aimed to investigate passive avoidance learning and memory in control and streptozocin-induced diabetic rats treated with an aqueous extract of Teucrium polium. Impairment in acquisit...

Teucrium polium can reduce serum glucose. There are few reports in the literature related to this subject and the resolution of this mechanism requires further experiments. The aim of the present study was to evaluate the effects of Teucrium polium aerial parts extracts on oral glucose tolerance tests and pancreas histology in streptozocin-induced diabetic rats. In order to prepare the aqueous ...

background: “teucrium polium l.” (tp) has been long recommended in iranian folk medicine for its anti-diabetic activities. we attempt here to evaluate the effect of tp extract on insulin secretion in rat pancreas. methods: rat pancreas was isolated in situ and perfused with krebs solution containing low glucose (lg, 2.8 mm) or high glucose (hg, 16.7 mm) as perfusate. the aqueous extract (aq. e)...

The ethanol extract of Teucrium manghuaense grown in Hainan province (China) was analysed by GC and GC/MS. Of the constituents 84-96% were identified on the basis of their GC retention times and their mass spectra in regard to authentic compounds. The results revealed that it contained 9-methyl-9-azabicyclo[4.2.1]nonane (7.43%), 2-methylpyrrolidine (19.42%), 3,7,11,15-tetramethyl-2-hexadecen-1-...

BACKGROUND Cognitive impairment occurs in diabetes mellitus. Teucrium polium L. (Lamiaceae) has been used in folk medicine to improve mental performance. Here we hypothesized that chronic treatment with an aqueous extract of Teucrium polium (100, 200 and 400 mg/kg, p.o.) would have an effect on passive avoidance learning (PAL) and memory in control and streptozocin-induced diabetic rats. MATE...