نتایج جستجو برای: tetrasubstituted imidazoles
تعداد نتایج: 4152 فیلتر نتایج به سال:
a series of tri- and tetra- substituted imidazoles were synthesized from benzyl, aldehyde and ammonium acetate in the presence of zeolite as an ecofriendly reusable catalyst under microwave irradiation in the absence of solvent. the yields are high to excellent and the use of microwave irradiation reduces reaction times to few minute.
An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times, mild conditions, simplicity of operation and easy work-up are some advantages of this protocol.
An efficient, simple, and green four-component reaction for synthesizing 1,2,4,5-tetrasubstituted imidazoles is developed. In present work exploring the use of Samarium triflate as a heterogeneous catalyst aldehydes, aromatic amines, benzil, ammonium acetate. The current approach offers many advantages, such excellent yields, shortening time, reusability catalyst, mild conditions.
A simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (SiO2-OSbCl2) as a catalyst in ethanol at moderate temperature. Operational simplicity, practicability and applicabi...
a convenient and efficient one-pot four-component synthesis of 1, 2, 4, 5-tetrasubstituted imidazoles using nano tio2 as a recyclable catalyst is reported. the results show that the methodology has several advantages such as low loading of catalyst, excellent yield, short reaction time, operational simplicity and solvent-free conditions.
Kaolin-SO3H as a new solid acid is prepared via reaction of kaolin and chlorosulfonic acid. This natural based catalyst is very inexpensive and easy available. Imidazoles are an important class of heterocycles being the core fragment of different natural products and biological systems such as anti-allergic, anti-inflammatory, analgesic, antifungal, antimycotic, antibiotic, antiulcerative, anti...
A series of new tetrasubstituted imidazoles 2-phenyl-3-(1, 4, 5-triphenyl-1H-imidazol-2-yl)-1H-indole derivatives substituted with –F, Cl, Br, I,-OCH3 and -NHCOCH3 were synthesized using a multicomponent reaction. The compounds were obtained in good yields by easy workup and with high purity
kaolin-so3h as a new solid acid is prepared via reaction of kaolin and chlorosulfonic acid. this natural based catalyst is very inexpensive and easy available. imidazoles are an important class of heterocycles being the core fragment of different natural products and biological systems such as anti-allergic, anti-inflammatory, analgesic, antifungal, antimycotic, antibiotic, antiulcerative, anti...
Kaolin-SO3H as a new solid acid is prepared via reaction of kaolin and chlorosulfonic acid. This natural based catalyst is very inexpensive and easy available. Imidazoles are an important class of heterocycles being the core fragment of different natural products and biological systems such as anti-allergic, anti-inflammatory, analgesic, antifungal, antimycotic, antibiotic, antiulcerative, anti...
A convenient and efficient one-pot four-component synthesis of 1, 2, 4, 5-tetrasubstituted imidazoles using nano TiO2 as a recyclable catalyst is reported. The results show that the methodology has several advantages such as low loading of catalyst, excellent yield, short reaction time, operational simplicity and solvent-free conditions.
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