Terpentecin and clerocidin, microbial terpenoides, have been known to be potent antitumor antibiotics. However, the critical biochemical target of these terpenoides has not been identified. Our present studies, using purified mammalian topoisomerase II, have shown that terpentecin and clerocidin induce topoisomerase II-mediated DNA cleavage in vitro with comparable potency to that of demethylep...

The genus Astragalus is a rich source of a variety of biologically active compounds including phenols, saponins, polysaccharides and essential oils. The present study was conducted to determine ontogenetic variation of the volatile organic compounds as well as total phenolic contents and antioxidant activity in leaves of A. compactus. The leaves of plant were harvested at vegetative, flowering ...

The soluble carrier proteins, OBPs carry odor components through sensilium lymph to specific receptors within the antennal sensilla to trigger behavioral responses. Herein, McinOBP4 was characterized from the Macrocentrus cingulum, which is the specialist parasitic insect of Ostrinia furnacalis for better understanding of olfactory recognition mechanism of this wasp. The classical odorant bindi...

abderaz the composition of the essential oil obtained from the seeds of ammi majus l. which collected from province of khozestan in the southwest area of iran.the oils was analyzed by gas chromatography mass spectrometry (gc-ms). twenty - eight components have been identified in the extract of a. majus l. with toluene (3.766%), thymol (12.811%), carvacrol (37.811%) as major components, respecti...

Background: The quest for organic agriculture has necessitated the search natural products which are abundant in phytochemicals and have significant therapeutic effects. This study was carried out to investigate nutritional ethno-medicinal potentials of egg-lime-molasses mixture (ELM). Methods: Fresh eggs were placed a bowl after 1 liter lime juice 500 g molasses added into same bowl, then it c...

Pseudognaphalium gaudichaudianum (DC.) Anderb., (Asteraceae) es una pequeña planta herbácea que crece en las alturas y lugares montañosos, conocida con el nombre vernacular de “Wira Wira”. Tiene buena reputación la medicina tradicional comunidades aimaras tierras altas Bolivia para tratar enfermedades respiratorias como tos, resfriado común, bronquitis neumonía. Por sus propiedades expectorante...

O objetivo deste trabalho foi determinar os constituintes químicos da farinha extrusada de sorgo (FES) do genótipo BRS 305 empregando-se a espectrometria massas com ionização por paper spray (PS/MS), um método que apresenta alta precisão, sensibilidade e possui baixo custo operação. Foram preparados extratos metanólicos partir amostra posteriormente avaliados nos modos positivo negativo. No mod...