Introduction: Previous studies have shown that exercise enhances cognitive and functional capacities in patients with Alzheimer's disease (AD). In this study, we investigated the effect of long-term (60 days) and short- term (10 days) exercise on the spatial memory deficits in an animal model of AD. Methods: Fifty male rats were divided into 5 groups 1) intact, 2) sham, 3) sham-Alzheimer 4) ...

objective: for decades, exercise has been considered as a cornerstone for managing diabetes. the current study aimed to determine the effects of short-term exercise on blood glucose, lipids and hba1c in type-2 diabetes mellitus. materials and methods: a total of 61 diabetic patients were randomly selected. later, subjects with capability of doing exercise took part in a special four-week exerci...

introduction: previous studies indicate that exercise influences cognitive function. nevertheless, considering that exercise in animal study can be voluntary, or forced, effects of exercise (specially forced exercise) on learning and memory abides as a matter of controversy. the present study aimed to investigate the effects of treadmill exercise on ltp in the dentate gyrus of rats. methods: th...

background: heavy exercise cause muscle damage associated with production of inflammatory agents. the purpose of present study was to determine the effect of acute and 14-day coenzyme q10 supplementation on inflammatory, blood lactate and muscle damage in male middle-distance runners.   methods : eighteen male middle-distance runners in a randomized and quasi experimental study were allocated i...

the aim of this study was to investigate the effect of long-term garlic supplementation (500 and 1000 mg) on dna damage index resulting from exhaustive exercise in non-athlete students. 26 male non-athletes (mean+sd age 21±1.23 years, weight 69.38±8.28 kg and height 178.9±6.11 cm) were divided randomly into three groups: the placebo and 2 garlic supplementation groups (500 and 1000 mg/day) (the...

   Background & Objective:  Irisin is considered as a candidate to treat obesity and metabolic diseases. Therefore, the aim of this study was a systematic review and meta-analysis to define the effective modes of exercise on irisin concentration in adults.  Materials & Methods:  Google Scholar, PubMed, Medline, Scopus, Science Direct, and references lists of articles were searched until April ...

the aim of this study was to determine the short-term (1 session) and long-term (36 sessions) effects of various exercise training (endurance, sprint, and combined) on plasmatic indexes of muscle damages (lactate dehydrogenase, creatine kinase, and malondialdehyde). for this purpose, 40 young rats (3 months old) were randomly divided into four groups including control, endurance, sprint, and co...