methenamine salts have been traditionally used in the veterinary and human medicine, but its use is sometimes associated with some side effects.toxicopathological effects of methenamine salt have always been a major concern. there is scantly information available about the lesions of methenamine compound in embryo. the objective of this study was to determine the teratogenic effects of methenam...

A girl was born to a mother who had undergone treatment for epilepsy with carbamazepine during pregnancy. The infant had dysmorphic features and was physically and mentally retarded. We consider that the malformations were the result of the maternal treatment with carbamazepine.

The effect of the teratogen 2-amino-1,3,4-thiadiazole on glycogenesis and glycogenolysis was investigated in the fetal and neonatal rat liver. At day 15, 16, or 17 of gestation (sperm day = day 0) pregnant Sprague-Dawley rats received a single IP injection of an aqueous solution of aminothiadiazole. Dosages used were teratogenic (100 mg/kg maternal body weight) and nonteratogenic (10 mg/kg). At...