Teladorsagia circumcincta is a polygamous nematode that exhibits morphological polymorphism. Sex ratio is typically female biased and the male nematodes occur in association with the genetically similar, minor morphotypes Teladorsagia davtiani and Teladorsagia trifurcata. In experimental infections, sex ratio (proportion male) and the proportion of minor male morphs observed have been shown to ...

background: like several other parasites, teladorsagia circumcincta secretes or excretes urea, but nei-ther the rate of efflux nor the possible metabolic sources of the urea has been considered. methods: parasites were maintained by passage through sheep. urea efflux was measured using phe-nol/hypochlorite after treatment with urea aminohydrolase. the kinetics of creatine amidinohy-drolase and ...

Authors’ addresses: 1 Deviot Institute, Deviot, Tasmania 7275, Australia. 2 School of Human Life Sciences, University of Tasmania, Locked Bag 1320, Launceston, Tasmania 7250, Australia. 3 University Kuala Lumpur, Royal College of Medicine Perak, 3 Greentown Road, 30450 Ipoh, Perak, Malaysia. 4 Institute of Food, Nutrition and Human Health, Massey University, Private Bag 11222, Palmerston North,...

Bradykinin is a physiologically active peptide involved in vasodilation and smooth muscle contraction and is previously shown to be increased in gastrointestinal mucus during nematode challenge in sheep. Here, it is shown that bradykinin in the abomasum is positively correlated with both mast cells and globule leukocytes in the abomasum, and that all three of these parameters are negatively ass...

Substantial debate exists on whether the immune response between sheep resistant and susceptible to gastrointestinal nematodes can be differentiated into a Th1 and Th2 phenotype. The present study addresses the hypothesis that variation in resistance to Teladorsagia circumcincta between DRB1*1101 (associated with reduced faecal egg count and worm burden) carriers and non-carriers is due to a di...

Nematodes are one of the main impactors on health, welfare and productivity farmed animals. Teladorsagia circumcincta endemic throughout many sheep-producing countries, particularly in northern hemisphere, contribute to pathology economic losses seen farms. Control these nematode infections is essential heavily reliant chemotherapy (anthelmintics), but this has been compromised by development a...