purpose: to evaluate tear film status and refractive conditions during and one month after treatment of acne vulgaris with isotretinoin (accutane). methods: this prospective study was performed on 26 eyes of 13 known cases of acne vulgaris. all cases were referred by a dermatologist and were candidates for low dose isotretinoin (0.5 mg/kg). full anterior and posterior segment examination and ob...

purpose : the main ocular manifestation of rheumatoid arthritis is dry eye. lacritin is a secreted glycoprotein of tear and when applied topically in rabbits, it increased the volume of basal tear secretion. so the aim of this study was to compare lacritin level in rheumatoid arthritis (ra) and control group. methods : this cross-sectional study was done on 40 patients with ra and 48 healthy su...

purpose: dry eye syndrome is a multifactorial disorder of the tear film and ocular surface that results in eye discomfort, visual disturbance, and often ocular surface damage. studies suggest that the prevalence of clinically diagnosed dry eye syndrome (des) is 0.4%. to 0.5%, which is highest among women and the elderly. the burden of des can be substantial, affecting visual function, daily act...

in this research, the mechanical properties of seven types of nanofilm with differing amounts of silver and silver-clay particles were studied. the elasticity of modulus, tensile strength, toughness, elongation at break, tear strength and color of nanofilms were compared with those of ordinary ldpe film. results showed that the inclusion of nano particles increased the modulus of elasticity, te...

purpose: to evaluate and compare tear secretion and tear film instability following laser in situ keratomileusis (lasik) and laser assisted subepithelial keratectomy (lasek). methods: in a randomized clinical trial, 30 eyes of 15 patients underwent lasik and 30 eyes of 15 patients underwent lasek to correct myopia. tear secretion and tear film instability were tested preoperatively, 2 and 6 wee...

PURPOSE To demonstrate the feasibility of indirectly measuring the precorneal tear film thickness and pre- and postlens tear film (PLTF) thickness using optical coherence tomography (OCT). METHODS Central corneal thickness (C(1)) which includes the tear film (T) of both eyes of 40 non-contact lens wearers was measured using OCT after calibration. The mean age of the 40 subjects was 31.2 +/- 9...

Purpose. To assess the tear film quantity and correlate it with the quality and stability of the tear film in diabetics and compare them to age matched controls. Introduction. Diabetes affects tear film parameters in multiple ways. Poor metabolic control and neuropathy are postulated factors. To further understand how diabetes affects tear film parameters this study was conducted. Subjects and ...

Purpose The aim of the study was to quantify the isolated tear film adhesion error in a Goldmann applanation tonometer (GAT) prism and in a correcting applanation tonometry surface (CATS) prism. Methods The separation force of a tonometer prism adhered by a tear film to a simulated cornea was measured to quantify an isolated tear film adhesion force. Acrylic hemispheres (7.8 mm radius) used a...

Tear film stability can be assessed via a number of tools designed for clinical as well as research purposes. These techniques can give us insights into the tear film, and allow assessment of conditions that can lead to dry eye symptoms, and in severe cases, to significant ocular surface damage and deterioration of vision. Understanding what drives tear film instability and its assessment is al...

PURPOSE The purpose of this study was to test the association between tear film fluorescence changes during tear break-up (TBU) or thinning and the concurrent ocular sensory response. METHODS Sixteen subjects kept one eye open as long as possible (MBI), indicated their discomfort level continuously, and rated ocular sensations of irritation, stinging, burning, pricking, and cooling using visu...