Introduction: Swallowing disorder or dysphagia is a common complication after conventional total thyroidectomy. Traditional dysphagia therapy (TDT) has long been a routine rehabilitation program for patients with dysphagia; however, there is no evidence to support the efficacy of this approach in patients with post-thyroidectomy dysphagia. Regarding this, the purpose of the current study ...

Purpose: As patients with transfusion-dependent thalassemia (TDT) are living longer, novel morbidities being recognized. The purpose of this review is to summarize the current knowledge regarding prevalence and risk factors nephrolithiasis in TDT. Methods: A non-systematic, narrative literature published up August 2021 was conducted. Results: Nephrolithiasis has been reported 18% - 59% TDT, whi...

Abstract Older adults appear to experience high levels of sub-clinical emotional distress. Past literature has predominantly focussed on ameliorating suffering in individuals with diagnosed mental illnesses, while neglecting research investigating online therapies for enhancing wellbeing community-dwelling older adults. A potential therapy might be Dignity Therapy, a brief psychotherapy origina...

The addition of nontemplated (N) nucleotides to coding ends in V(D)J recombination is the result of the action of a unique DNA polymerase, TdT. Although N-nucleotide addition by TdT plays a critical role in the generation of a diverse repertoire of Ag receptor genes, the mechanism by which TdT acts remains unclear. We conducted a structure-function analysis of the murine TdT protein to determin...

OBJECTIVE To compare the outcome of an early application of neuromuscular electrical stimulation (NMES) combined with traditional dysphagia therapy (TDT) versus traditional dysphagia therapy only in acute/subacute ischemic stroke patients with moderate to severe dysphagia by videofluoroscopic swallowing study (VFSS). METHODS Fifty-seven dysphagic stroke patients were enrolled in a VFSS within...

The recombination rates in meioses of females and males are often different. Some genes that affect development and behavior in mammals are known to be imprinted, and >1% of all mammalian genes are believed to be imprinted. When the gene is imprinted and the recombination fractions are sex specific, the conventional transmission disequilibrium test (TDT) is shown to be still valid for testing f...

The transmission/disequilibrium test (TDT) is widely used to detect the linkage disequilibrium between a candidate locus (a marker) and a disease locus. The TDT is a family-based design and has the advantage that it is a valid test when population stratification exists. The TDT requires the marker genotypes of affected individuals and their parents. For diseases with late age of onset, it is di...