Although tau is a cytoplasmic protein, it is also found in brain extracellular fluids, e.g., CSF. Recent findings suggest that aggregated tau can be transferred between cells and extracellular tau aggregates might mediate spread of tau pathology. Despite these data, details of whether tau is normally released into the brain interstitial fluid (ISF), its concentration in ISF in relation to CSF, ...

this article presents a unified approach to the abstract notions of partial convolution and involution in $l^p$-function spaces over semi-direct product of locally compact groups. let $h$ and $k$ be locally compact groups and $tau:hto aut(k)$ be a continuous homomorphism.  let $g_tau=hltimes_tau k$ be the semi-direct product of $h$ and $k$ with respect to $tau$. we define left and right $tau$-c...

In this article the instability of single phase flow in a circular pipe from laminar to turbulence regime has been investigated. To this end, after finding boundary conditions and equation related to instability of flow in cylindrical coordination system, which is called eigenvalue Orr Sommerfeld equation, the solution method for these equation has been investigated. In this article Chebyshev p...

relative to a hereditary torsion theory $tau$ we introduce a dimension for a module $m$, called {em $tau$-rank of} $m$, which coincides with the reduced rank of $m$ whenever $tau$ is the goldie torsion theory. it is shown that the $tau$-rank of $m$ is measured by the length of certain decompositions of the $tau$-injective hull of $m$. moreover, some relations between the $tau$-rank of $m$ and c...

Abnormal tau aggregation is a pathological hallmark of many neurodegenerative disorders and it is becoming apparent that soluble tau aggregates play a key role in neurodegeneration and memory impairment. Despite this pathological importance, there is currently no single method that allows monitoring soluble tau species in living cells. In this regard, we developed a cell-based sensor that visua...

In this manuscript, the reliability of a robotic system has been analyzed using the available data (containing vagueness, uncertainty, etc). Quantification of involved uncertainties is done through data fuzzification using triangular fuzzy numbers with known spreads as suggested by system experts. With fuzzified data, if the existing fuzzy lambda–tau (FLT) technique is employed, then the comput...

this paper presents an operational formulation of the tau method based upon orthogonal polynomials by using a reduced set of matrix operations for the numerical solution of nonlinear multi-order fractional differential equations(fdes). the main characteristic behind the approach using this technique is that it reduces such problems to those of solving a system of non-linear algebraic equations....

The aggregations of tau protein in brain tissue have been described in a large number of neurodegenerative diseases; however, due to the lack of tau isoform- or exon-specific antibodies, the exact situations under which various brain tau isoforms can be found and their exact contributions during disease progression remain unknown. Therefore, in this study, we prepared tau exon-specific monoclon...

‎in this paper‎, ‎a spectral tau method for solving fractional riccati‎ ‎differential equations is considered‎. ‎this technique describes‎ ‎converting of a given fractional riccati differential equation to a‎ ‎system of nonlinear algebraic equations by using some simple‎ ‎matrices‎. ‎we use fractional derivatives in the caputo form‎. ‎convergence analysis of the proposed method is given an...