Orally Disintegrating Tablets (ODT) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. We focused on taste masking and formulation of ranitidine ODT which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

Orally Disintegrating Tablets (ODT) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. We focused on taste masking and formulation of ranitidine ODT which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

Taste-masking technologies are important for obtaining high-patient compliance and drug therapy efficiency, since many oral-delivery drugs have unpleasant qualities such as bitterness, sourness or saltiness. Taste-masking technology includes two aspects: selection of appropriate tastemasking substances (polymers, flavourings, sweeteners, amino acids, etc.) and selection of appropriate taste-mas...

ION EXCHANGE RESIN AS AN IMPOSING METHOD FOR TASTE MASKING: A REVIEW A. M. Suthar* and M. M. Patel Saraswati School of Pharmacy, Ranela, Gujarat, India Kalol Institute of Pharmacy, Kalol, Gujatat, India ABSTRACT Taste masking becomes a pre-requisite for bitter drugs to improve the patient compliance especially in the pediatric and geriatric population. Conventional taste masking techniques such...

Taste-masking techniques are applied to mask or overcome the bitter or unpleasant taste of active pharmaceutical ingredients/drugs to achieve patient acceptability and compliance. Oral administration of bitter or unpleasant tasting drugs is often the biggest barrier for patient groups, such as pediatrics and geriatrics.1 A survey of American Association of Pediatricians reports unpleasant taste...

orally disintegrating tablets (odt) have the advantages of both solid dosage form specially the stability and ease of handling and liquid dosage forms including ease of swallowing and pre-gastric absorption. we focused on taste masking and formulation of ranitidine odt which disintegrates rapidly in the mouth within 60 seconds using super-disintegrants, special polymers, water soluble and even ...

Taste of a pharmaceutical formulation is an important parameter for the effectiveness of pharmacotherapy. Cetirizine dihydrochloride (CET) is a second-generation antihistamine that is commonly administered in allergy treatment. CET is characterized by extremely bitter taste and it is a great challenge to successfully mask its taste; therefore the goal of this work was to formulate and character...

ions and is widely used to determine the activity and concentration of hydrogen ions. Metal ion-selective electrodes, such as potassium ions and calcium ions, are also commercially available. Drug ion selective electrodes are prepared and are used to determine the concentrations of drug ions. Other applications of drug ion electrodes include studies of protein binding of drug ions, mechanisms o...

The spray drying technique was used to obtain the roxithromycin containing microcapsules with high taste masking efficiency. Eudragit L30D-55 was chosen as a barrier coating. The taste was evaluated by an electronic tongue, and taste-masking effect in water lasted at least several dozen hours.

Acceptability of any dosage form are mainly depends over its taste i.e. mouth feel. Drug molecule interacts with taste receptor on the tongue to give bitter, sweet or salty taste sensation, when they dissolve in saliva. This sensation of the taste is the result of signal transduction from the receptor organs for taste, commonly known as taste buds. In market, there are numbers of pharmaceutical...