background: prostate cancer after lung cancer is the second cause of cancer-associated death in men. in recent years, targeted therapy of cancer has attracted researchers attention. the targeted therapy lead to decrease in side effects of drugs. studies have indicated that targeting peptides for cancer cells represent valuable tools for diagnostic and therapeutic. recently, phage display peptid...

Tumor-targeted therapies are playing growing roles in cancer research. The exploitation of these powerful therapeutic modalities largely depends on the discovery of tumor-targeting ligands. Phage display has proven a promising high throughput screening tool for the identification of novel specific peptides with high binding affinity to cancer cells. In the present study, we describe the use of ...

Tumor-targeted therapies are playing growing roles in cancer research. The exploitation of these powerful therapeutic modalities largely depends on the discovery of tumor-targeting ligands. Phage display has proven a promising high throughput screening tool for the identification of novel specific peptides with high binding affinity to cancer cells. In the present study, we describe the use of ...

Multifunctional micelles based on a peptide–polymer for simultaneously targeting A? degradation and ROS scavenging AD therapy.

Peptide-based strategies have received an enormous amount of attention because their specificity and applicability. Their tumor-targeting ability are applied to diagnosis treatment for cancer patients. In this review, we will summarize recent advancements future perspectives on peptide-based treatment. The literature search was conducted identify relevant articles It performed using PubMed in E...

objective: recently, phage display libraries have received enormous attention for identification and isolation of pharmaceutical molecules with diagnostic and therapeutic properties. peptide libraries are known as one of the most important and widely used types of phage display libraries. in the current study, we aimed to screen the ph.d.tm-7 phage display peptide library through biopanning for...

Peptide Navigators In article number 2110368, Chang-Soo Kim, Hak-Joon Sung, and co-workers introduce a peptide navigator for vascular nanotheranostics. The display of disturbed flow-sensing peptides on nanoparticles enables accurate prediction pre-stenotic vessels with subsequent prevention remodeling through multi-organ targeting. results from in vitro vivo models validate an unprecedented nan...

Peptide Nanofibers In article number 2300673, Lei Wang, Xing-Lou Yang, Hao Yuliang Zhao, and co-workers introduce innovative nanofibers targeting the viral spike protein of SARS-CoV-2. Using a highthroughput screening approach, peptide are designed prepared that efficiently entangle virus, forming network inhibiting its interaction with host cells' ACE2 receptors. This nanomedicine exhibits sig...

Combination of RGD cell adhesion peptide with GHK modulator synergistically improves targeting tumor cells. Amphiphilic peptides can be effectively displayed on liposomal surface for screening and drug delivery applications.

Mitochondria are vital organelles to eukaryotic cells. Damage to mitochondria will cause irreversible cell death or apoptosis. In this report, we aim at programmed cancer cell death via specific mitochondrial damage. Herein, a functionalized pro-apoptotic peptide demonstrates a dual-targeting capability using folic acid (FA) (targeting agent I) and triphenylphosphonium (TPP) cation (targeting a...