نتایج جستجو برای: targeted therapy

تعداد نتایج: 776661  

Journal: :gene, cell and tissue 0
janella hudson department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states teresita munoz-antonia department of tumor biology, h. lee moffitt cancer center and research institute, tampa, united states eric haura department of thoracic oncology, h. lee moffitt cancer center and research institute, tampa, united states; department of oncologic science, morsani college of medicine, university of south florida, tampa, united states doug cress department of molecular oncology, h. lee moffitt cancer center and research institute, tampa, united states vani n. simmons department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states; department of oncologic science, morsani college of medicine, university of south florida, tampa, united states gwendolyn p. quinn department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states; department of oncologic science, morsani college of medicine, university of south florida, tampa, united states; department of health outcomes and behavior, h. lee moffitt cancer center and research institute, tampa, united states. tel: +1-8137451359

Journal: :iranian journal of nuclear medicine 2009
mohamadreza nouri mahdavi

neuroendocrine tumors (nets) constitute a heterogeneous group of neoplasms including carcinoids, pancreatic neuroendocrine tumors, pituitary tumors, medullary thyroid carcinoma and phaeochromocytomas. the symptoms and the outcome of nets differ considerably between patients depending on several factors. by labelling tracers with a radioisotope, the tracer acts as a carrier to deliver the radioa...

Journal: :razavi international journal of medicine 0
narges jafarzadeh department of research and education, razavi hospital, mashhad, ir iran hami ashraf department of research and education, razavi hospital, mashhad, ir iran; zakaria idea and innovation support and leading center, tehran, ir iran fahimeh khoshroo department of research and education, razavi hospital, mashhad, ir iran alireza sepehri shamloo student research committee, mashhad university of medical sciences, mashhad, ir iran farzad bidouei department of research and education, razavi hospital, mashhad, ir iran kamran ghaffarzadehgan department of research and education, razavi hospital, mashhad, ir iran; department of research and education, razavi hospital, mashhad, ir iran. tel: +98-5116004594, fax: +98-5116668883

context triple negative breast cancer (tnbc) is a heterogeneous group of diseases that is negative for esterogen receptor (er) progesteron receptor (pr) and human epidermal growth factor receptor 2 (her2). this type of breast cancer is typically high-grade carcinomas, although low-grade tumors occur. the aim of this review is to focus on molecular classification and features, prognostic markers...

Journal: :iranian journal of public health 0
mohammad amir mishan asieh heirani-tabasi neda mokhberian malihe hassanzade hamid kalalian moghaddam ahmad reza bah­rami

background: chemokine receptors have been shown to play an important role in the development and metastatic spread of various malignancies. in this study, the gene expression profile of some key chemokine receptors involved in metastasis has been investigated in esophageal and breast cancer cell lines.   methods: in a descriptive study, gene expression profile of ccr1, ccr6, ccr7, ccr9, cxcr1, ...

Alireza Rafiei, Forough Nejatollahi, Mohsen Tehrani, Reza Valadan,

Production and approval of trastuzumab (Herceptin®) for the treatment of metastatic breast cancer (MBC) was a millstone in antibody-based targeted therapy in the cancer treatment. However, despite the early success in the clinical trials, trastuzumab failed to appreciate the initial attraction due to development of resistance to the drug. The majority of patients who benefit from the drug...

Bahareh Kashani, Mohammadreza Noori-Daloii,

Cancer is one of the most dangerous health problems of today modern societies which has an increasing rate especially in developing countries. There are many diverse ongoing treatment attempts trying to defeat cancer. Despite that, scientists have been unable to find a permanent cure for this disease. In many cases although there is a successful first response in patients, cancer cells are fina...

2016
I Lupu N Voiculescu N Bacalbasa I Cojocaru V Vrancian C Giurcaneanu

The new molecular targeted therapy has been developed over the past decades by using the molecular targeted molecular changes discovered in specific types of cancer. Unfortunately, most of these agents (epidermal growth factor receptors, multi-targeted small molecule tyrosine kinase inhibitors, monoclonal antibodies) have severe cutaneous adverse reactions, that not only interfere with the pati...

Journal: :iranian journal of cancer prevention 0
abdolali ebrahimi dept. of pathology, shahid beheshti university of medical sciences, tehran, iran laila larijani cancer research center, shahid beheshti university of medical sciences, tehran, iran afshin moradi cancer research center, shahid beheshti university of medical sciences, tehran, iran mohamad reza ebrahimi red crescent society of islamic republic of iran, tehran, iran

hedgehog signalling pathway has not only a critical role in cell proliferation, differentiation and tissue polarity at embryonic period but also has a vital role in stem cell proliferation, tissue healing and carcinogenesis. recent research has increased our understanding of this pathway and its relation to other signalling pathways. in addition, a large number of studies confirmed the alterati...

Journal: :modares journal of medical sciences: pathobiology 2011
fatemeh safarian fatemeh rahbarizadeh said amanpour zahra sharifzadeh

objective: the objective of this study is to develop and assess targeted pamam-peg nanocarrier with anti-tag72 nanobody for t-bid gene coding construct delivery into the human colonic adenocarcinoma cells. materials and methods: nanobody (nb) coding sequence was subcloned into psj expression vector for large-scale production and then nb was purified by ni++ affinity chromatography. sds-page an...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سمنان - دانشکده علوم تربیتی و روانشناسی 1391

anxiety is one common disorder during childhood. in curing anxiety disorders, there are different types of psychological remedies, pharmotherapy, family therapy, and music therapy that can improve the individual’s anxiety, but we need some other remedies to improve social and emotional relationship and interactions. considering the importance of curing the anxiety disorders, the effect of sand ...

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