background: vitamin d deficiency may play a key role in the development of impaired glucose tolerance, type 2 diabetes mellitus (t2dm), and metabolic syndrome. several studies have shown that vitamin d has an antioxidant property. we aimed to investigate 25?hydroxy vitamin d (25[oh]d) levels in patients with t2dm and in nondiabetic healthy controls and to ascertain the impact of 25(oh)d levels ...

six months administration of bromocriptine mesylate significantly decreased glycated hemoglobin (hba1c), fasting blood sugar, postprandial blood sugar, and weight of 22 indian obese patients with type 2 diabetes mellitus with no serious adverse events. therefore, the novel mechanism of action, efficacy and acceptable safety profile makes this drug an attractive option for treatment of obese typ...

conclusions improvement of biomarkers of insulin sensitivity, including adiponectin and lipid metabolism, is an important therapeutic effect of medical nutrition therapy in obese patients with t2dm. objectives we evaluated the effects of calorie-restricted diet therapy on the circulating level of the serum lipid profile, glucose, insulin, and adiponectin in obese women with t2dm. materials and ...

type 2 diabetes mellitus (t2dm) is recognized as a public health problem and increasingly prevalent illness. key elements of the guideline for diabetes care are based on evidence-based medicine approach and apply for population, not individuals. however, individualized care can improve diabetes management. personalized medicine is otherwise called precision medicine tries to find better predict...

Type 2 diabetes mellitus (T2DM) is one of the most common multifactorial disorders in Iran. Recent genome wide association studies (GWASs), and functional studies have suggested that WFS1 may predispose individuals to T2DM. However, to date, the possible association of such variants with T2DM in Iranians remained unknown. Here, we investigated the association of the two polymorphisms of WFS1 (r...

background the altered levels of some essential trace elements and antioxidant minerals have been observed in diabetic patients. objectives the aim of the present study was to compare the concentrations of essential trace elements, copper (cu), zinc (zn), and iron (fe) in the serum of patients who have type 2 diabetes mellitus (t2dm) with those of their non-diabetic first-degree relatives (fdr)...

conclusions our study indicated that ace-d and vegf-g alleles can be an independent risk factor for microalbominuria in t2dm patients. results a total of 255 consecutive patients with t2dm and microalbuminuria (group a) and 235 patients with t2dm and normoalbuminuria (group b) were included in the study. in univariate analysis, the groups were statistically similar for all variables, except for...

Background: Type II Diabetes mellitus (T2DM) is a multifactorial disease and a leading cause of premature deaths. Inflammatory cytokines are reported that they have potential to enhance insulin resistance and hence T2DM. Assessment of immunological profile in T2DM patients of Kashmir valley is unclear. So, detection of cytokines is relevant to determine the extent and direction of immune respon...

type 2 diabetes mellitus (t2dm) occurs around the world with high prevalence and causes serious physical harm and economic burden to the afflicted. haikou city is china's southernmost tropical island city, which has not been previously studied for its t2dm prevalence. the objective of the study in employing a cross-sectional survey is to discuss the epidemiologic status of t2dm in haikou city a...