Journal:
:iranian journal of basic medical sciences
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mohsen imenshahidi pharmaceutical research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran
bibi marjan razavi targeted drug delivery research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran
ayyoob faal school of pharmacy, mashhad university of medical sciences, mashhad, iran
ali gholampoor school of pharmacy, mashhad university of medical sciences, mashhad, iran
seyed mehran mousavi school of pharmacy, mashhad university of medical sciences, mashhad, iran
hossein hosseinzadeh pharmaceutical research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, iran
objective(s): in this study, the effects of chronic administration of crocin, an active constituent of saffron, on blood pressures of normotensive and desoxycorticosterone acetate (doca) - salt induced hypertensive rats, were investigated. materials and methods: five week administration of three doses of crocin (50, 100 and 200 mg/kg/day) and spironolactone (50 mg/kg/day) in different groups ...