conclusions this report aimed to increase awareness of the occurrence of extra-intestinal systemic manifestations of rotavirus infection. although such cases may be rare, they still suggest that that rotavirus is a systemic viral infection. case presentations we report three pediatric cases of rotavirus infection: one accompanied by encephalopathy and two with elevated hepatic transaminase acti...

conclusions this paper highlighted the need to exclude csd in children with unexplained symptoms such as prolonged fever, hepatosplenic lesion and osteomyelitis. case presentation we reported a series of seven children with unusual symptoms of csd. in particular, we described the case of a child with ptosis, miosis and enophtalmy, suggesting horner syndrome, associated with cervical lymphadenit...

hemophagocytic syndrome (hps) is an uncommon manifestation in systemic lupus erythematosus (sle). clinical features of hps include fever, pancytopenia, abnormal liver enzyme, hepatosplenomegaly, lymphadenopathy, and coagulation disorder. hps comprises primary and reactive forms. herein, we describe a case of untreated sle with hps as one of the first manifestations of systemic lupus.

We hereby report a 79-year-old Iranian man presenting with nail dystrophy and subsequent development of purpuric and ecchymotic plaques, hemorrhagic bullae, and infiltrated papules on the head, neck and trunk. Histological examination of the gingiva, bone marrow aspiration, and biopsy confirmed the diagnosis of primary systemic amyloidosis. In this case, nail dystrophy was the presenting sign o...

Scorpion bite is common in rural areas of India with self limiting local reaction and pain at envenomation site, however envenomation due to Mesobuthus tamlus (Indian red scorpion) some time have uncommon systemic manifestation like myocarditis, pulmonary edema, pancreatitis, defibrination syndrome, DIC and CNS manifestation due to hemorrhagic infarct, all these systemic manifestation is corrob...