thymoma is a term that should be restricted to neoplasms of thymic epithelial cells, irrespective of the presence or the number of lymphocytes. the usual location of thymoma is the antrosuperior mediastinum; however, this tumor can also occur in other mediastinal compartments, in the neck, within the thyroid gland, in the pericardial cavity, the pulmonary hilum, within the lung parenchyma, or t...

Background: Systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. The importance of some genes in the development of systemic lupus erythematosus has been implicated. The gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has ...

lupus erythematosus (le) is an autoimmune disease. the mortality rate and causes of death are different in various countries. the present study is done to find out the causes of mortality in the systemic lupus erythematosus (sle) patients in lupus unit of rheumatology research center and other wards of shariati hospital. this study was retrospective according to medical records of patients who ...

at present, some clinical presentations and serological parameters such as products of complement activation and elevation of autoantibodies (e.g. dsdna antibodies), erythrocyte sedimentation rate (esr), levels of c-reactive protein (crp), or cytokines such as il-2/il-2 receptor, il-6 and il-10 are used as indirect serological markers with variable degrees of significance. to date, no specific ...

the central immunological disturbance in systemic lupus erythematosus (sle) is autoantibody production. some of these antibodies affecting components of the cell nucleus are the major characteristics of sle. the present study was aimed to assess importance of anticardiolipin (acl) antibody and its association with clinical state in sle patients. a cross sectional study was performed on 100 pati...

background: systemic lupus erythematosus (sle) has various presentations in children. hematologic abnormalities is common in childhood onset of sle, however, isolated thrombocytopenia is relatively rare. thus, we present a child with isolated thrombocytopenia as a rare presentation of sle. case presentation: a 12-year-old boy with chief complaints of loss of appetite, weight loss, decreased pla...

a twelve year old girl, an established case of systemic lupus erythematosus, was referred to us suffering from diplopia and nasal speech for a period of 3 months. neurological examination was conducted which revealed a right-sided sixth nerve palsy and a pulsatile nasopharyngeal mass. neurodiagnostic imaging studies confirmed a giant intracavernous internal carotid aneurysm. the malady of the a...

background: systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. the importance of some genes in the development of systemic lupus erythematosus has been implicated. the gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has b...

central nervous system ranks among the favorite sites to get involved by nocardia astroides. this opportunistic organism complicates many disorders characterized by cellular or humoral immunity disturbances.a 36-year-old woman is being presented, known to have systemic lupus erythematosus (sle) and having received a two year course of corticosteroid treatment. cerebellar abscess was found on di...