background sepsis can be defined as the body’s response to an infection. sepsis in children remains a significant cause of morbidity and mortality worldwide. objectives this study focuses on the etiological factors, risk factors, and clinical characteristics of sepsis in neonate and pediatric patients. patients and methods a prospective study was conducted over a six-month period in the pediatr...

procalcitonin (pct) is a precursor peptide for the hormone calcitonin and is frequently increased in overt sepsis. the aim of this study was to test diagnostic accuracy of procalcitonin among patients with positive systemic inflammatory response syndrome (sirs) in identifying sepsis. in this cross sectional study, from 563 patients with positive sirs admitted through the emergency department of...

background procalcitonin (pct) levels are increased in sepsis. in most previously conducted research, pct levels were found to increase during septic shock. objectives the purpose of this study was to compare pct levels with crp and esr levels in children with systemic inflammatory response syndrome (sirs), sepsis, and septic shock. methods this cross-sectional study was conducted between decem...

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

background one of the main components involving in the pathogenesis and prognosis of sepsis and septic shock is natriuretic peptide. hemodynamic changes in sepsis or septic shock might explain increased plasma levels of these peptides circulations. objectives the present study aimed to assess the value of brain natriuretic peptide (bnp) in prediction of sepsis state and its related morbidity. w...

hemophagocytic lymphohistiocytosis (hlh) is one of the complications of epstein-barr virus (ebv) infection. although the patients who have developed hlh following ebv have normal immune system, there are a few patients with ebv-induced immune deficiency who develop hlh as well. here, we describe the case of a 10-year-old girl with neurological complications caused by ebv-induced hlh. the patien...

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conclusions this study shows that an adequate nutritional support, in patients with severe burn injury, can improve sofa score. it is also more cost-effective, resulting in a shorter los in hospital. background severe burned patients developed metabolic imbalances and systemic inflammatory response syndrome (sirs), which can lead to malnutrition, impaired immunologic response, multiple organ fa...