introduction autoimmune haemolytic anemia (aiha) is a complex process characterized by an immune reaction against red blood cell self-antigens. the analysis of specimens, drawn from patients with cold auto-immune hemolytic anemia is a difficult problem for automated hematology analyzer. this paper was written to alert technologists and pathologists to the presence of cold agglutinins and its ef...

Regular physical activity can affect the haematological parameters on an individual. This study was aimed at assessing and CD4 of young sportspersons (pre-and post-exercise) in Ambrose Alli University, Ekpoma, Nigeria. A total fifty healthy between 16-28 years age both sexes were recruited for this study. The analyzed using Sysmex KX-21N haematology autoanalyzer while counts determined by flow ...

Dear Editor The recently launched hematology autoanalyzer Sysmex XN2000 (Sysmex, Kobe, Japan) provides a new method (PLT-F method) for platelet counting based on a fluorescent RNA staining dye named oxazine [1, 2]. The main advantage of the XN2000’s PLT-F method over the former instrument XE-2100’s optical method (PLT-O method) is the ability to identify apoptotic white cells and not count them...

Immature Granulocytes (IG) are normally not present in peripheral blood. Their presence is an important indicator of enhanced bone marrow activation. The present study evaluated the diagnostic performance of the Sysmex XT-2000i automated hematology analyzer in the detection of myelocytes and/or metamyelocytes in patients affected by non-haematological disease, in comparison with manual microsco...

OBJECTIVES This study compared the new high-volume blood coagulation analyzer Sysmex CS-5100 System™ (Siemens Healthcare Diagnostics, Erlangen, Germany) to the mid-volume blood coagulation analyzer Sysmex CS-2000i System™ (Siemens) for analytical performance. Additionally, the operational performance of the Sysmex CS-5100 System was compared with the blood coagulation analyzer ACL TOP 700 (Inst...

This study investigated the immature platelet fraction (IPF) in assessing treatment effects in immune thrombocytopenia (ITP). IPF was measured on the Sysmex XE2100 autoanalyzer. The mean absolute-IPF (A-IPF) was lower for ITP patients than for healthy controls (3.2 vs 7.8 × 10⁹/L, P < .01), whereas IPF percentage was greater (29.2% vs 3.2%, P < .01). All 5 patients with a platelet response to E...

INTRODUCTION Full blood count (FBC), one of the most frequently requested for laboratory investigations, is a simple, fast and cheap test and is a reliable indicator of health. Due to its usefulness in the assessment of health status of individuals, its parameters in cord blood, a major source of haemopoietic stem cell transplantation and an ideal source for laboratory investigations for newbor...

The pandemicity of coronavirus disease 2019 (COVID-19) necessitated its novel biomarkers in prognosis and monitoring low resource settings. Changes total white blood cell counts have been associated with the progression diseases. This study determined prognostic value some cellular inflammatory cells their indices relation to duration hospital admission, gender, age COVID-19 patients. longitudi...

BACKGROUND Coronary artery disease is mainly caused by atherosclerosis and its complications. Platelets and their activity have an important role in initiation of atherosclerotic lesions and coronary thrombus formation. Larger platelets are enzymatically and metabolically more active and have a higher potential thrombotic ability as compared with smaller platelets. AIMS To study the changes i...

We compared the accuracy and precision of the impedance platelet counts generated by the Beckman Coulter LH 750 and the Sysmex XE 2100 and the optical platelet counts produced by the Advia 120 and the Sysmex XE 2100 withflow cytometric reference platelet counts. Samples analyzed had platelet counts less than 150 x 10(3)/microL (150 x 10(9)/L) with a platelet flag or less than 75 x 10(3)/microL ...