Synaptic Transistors In article number 2200733, Ye Zhou and co-workers design a multi-terminal MoS2 synaptic transistor to mimic the parallel signal transmission behaviors of biological multipolar neurons. With combination microstructured pressure sensors, an intelligent tactile recognition system is built up realize spatiotemporal modulation plasticity.

Many chemicals with broad industrial, pharmaceutical and agricultural application produce a neurotoxic syndrome in humans and experimental animals involving weight loss, skeletal muscle weakness and ataxia. Neurotoxicity is defined as a structural change or a functional alteration of the nervous system resulting from exposure to a chemical, biological or physical agent. Neurotoxicity including ...

Astrocyte cells form the largest cell population in brain and can influence neuron behavior. These provide appropriate feedback control regulating neuronal activities Central Nervous System (CNS). This paper presents a set of equations as model to describe interactions between neurons astrocyte. A VHDL–AMS-based tripartite synapse that includes pre-synaptic neuron, synaptic terminal, post-synap...

Neuromorphic computing (NC) is a crucial step toward realizing power-efficient artificial intelligence systems. Hardware implementation of NC expected to overcome the challenges associated with conventional von Neumann computer architecture. Synaptic devices that can emulate rich functionalities biological synapses are emerging. Out several approaches, electrolyte-gated synaptic transistors hav...

glutamatergic system stimulationthe nucleus accumbens shell, may affect anxiety-related behaviors, aversive learning and memory. glutamate receptors are differentially distributed in pre- and postsynaptic sites contributing to neuronal communications.the present study aimed to examine the possible involvement of the nac shell presynaptic nmda receptors on nmda induced responses, using the eleva...

The emulation of synaptic responses with memristors is an attractive route to neuromorphic networks. A hybrid conjugated polymer pendant carbazole rings was employed in a two-terminal memristor that exhibited synergistic percolation mechanisms.

the purpose of this study was to investigate the effects of 8 weeks of endurance training (et) on ? -1a protein of pre-synaptic p-q-type calcium channels in fhl and soleus muscles of rats. 16 male wistar rats provided from razi institute, were randomly divided to 2 groups (control-sham; n=8 and endurance training; n= 8). training group performed 8 weeks (5 session/week) of endurance training on...

The question of whether the synaptic extracellular matrix undergoes remodeling and how this remodeling is related to nerve terminal plasticity was examined in living neuromuscular junctions of adult frogs. Sartorius muscles were double stained with a fluorescent nerve terminal dye 4-(4-diethylamino-styryl)-N-methylpyridinium iodide (4-Di-2-Asp) and rhodamine-tagged peanut agglutinin (PNA) which...

Remodeling of the synaptic extracellular matrix (ECM) and its dynamic relationship with nerve terminal plasticity have been demonstrated in normal frog neuromuscular junctions (NMJs) in vivo (Chen et al., 1991). Our previous work has led to a hypothesis that extension of synaptic ECM precedes nerve terminal growth during synaptic remodeling. To test this hypothesis, the present study examined t...