نتایج جستجو برای: sustained virological responses
تعداد نتایج: 476190 فیلتر نتایج به سال:
results the analysis of data for c/t snp showed that the cc genotype is more common in the control group than in the group of patients. in contrast, the frequency of tt as a mutant genotype is more frequent in patients than in uninfected people. in addition, results showed a statistically significant relationship between cc, ct, and tt genotypes in sensitive and resistant groups (p value: < 0.0...
ABSTRACT Background: Combination therapy with interferon and ribavirin is the most effective treatment for chronic hepatitis C today. The aim of this study was to evaluate the efficacy and safety of thrice-weekly Heberon (interferon alfa-2b) in combination with ribavirin as first -line treatment of chronic hepatitis C. Methods: A total of97 treatment-naive patients received Heberon three milli...
abstract background: combination therapy with interferon and ribavirin is the most effective treatment for chronic hepatitis c today. the aim of this study was to evaluate the efficacy and safety of thrice-weekly heberon (interferon alfa-2b) in combination with ribavirin as first -line treatment of chronic hepatitis c. methods: a total of97 treatment-naive patients received heberon three millio...
results patients who attained sustained virological response had a less risk (85%) for all-cause mortality and about 63% reduced risk of hepatocellular carcinoma incidence than those who did not achieve sustained virological response. based on deeply analysis, the stage of liver fibrosis was a risk factor at baseline for the incidence of hepatocellular carcinoma. conclusions sustained virologic...
Direct-acting antivirals (DAAs) in combination with pegylated IFN-a and ribavirin drastically improve the rates of rapid virological response (RVR) and sustained virological response (SVR) in the treatment of chronic hepatitis C virus infection, specifically in difficult-to-cure hepatitis C virus genotype 1. At present, RVR is an important milestone highly predictive of SVR. Response-guided the...
Background Although the ideal end point of chronic HBV hepatitis therapy is HBsAg loss, a realistic end point is the induction of sustained virological remission. The definitions of virological responses vary according to therapeutic regimen: viral load <2000 IU/mL after interferon (IFN) regimens and undetectable HBV-DNA during nucleoside/nucleotide analogues (NNA) regimens. Objective: To compa...
A phase 2 study of an interferon-free combination daclatasvir (BMS-790052, Bristol-Meyers Squibb) plus GS-7977 (formerly PSI-7977, Pharmasset/Gilead), with or without ribavirin, showed that this regimen was well tolerated and that treatmentnaive patients with hepatitis C virus (HCV) genotype 1, 2, and 3 infection achieved high rates of early sustained virological responses (SVRs). Investigators...
conclusions examination of the fasting lipid profile has clinical importance in predicting the efficacy of peg-ifn-α-2b plus rbv combination therapy for patients with hcv g1b even after the discovery of the il28 genotype as a potent predictive factor. objectives to re-examine the significance of lipoprotein profiles on virological response to peg-ifn plus rbv combination therapy in patients wit...
conclusions our findings indicate that patients with the homozygous cc genotype in the il28b gene had a significantly higher rate of response to treatment than those with the tt or ct genotypes. nor does the il28b rs12979860 polymorphism affect the viral load. results the genotype frequencies of rs12979860 polymorphism in group 1 were cc (28.9%), ct (37.8%) and tt (33.3%) and in group 2 were cc...
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