background: increasing the complexity in modern radiotherapy techniques have increased the delivery time lowering consequently the treatment efficacy. through simulating the delivery time delay encountered in such techniques, its’ effect on two cancer cell lines and the compensating doses given to prevent such effect was investigated. materials and methods: f10b16 and 4t1 cancer cell lines were...

background: various mtt assay methods are proposed to obtain the cell sur- vival parameters. objective: determining the survival curve characteristics of two cancerous cells of interest based on a common and a novel mtt assay method after exposing them to ionizing radiation. method: a common and a novel mtt assay method were used and compared for obtaining the f10b16 melanoma and 4t1 breast ade...

abstract background: hyperthermia (also called thermal therapy or thermotherapy) is a type of cancer treatment in which body tissue is exposed to high temperatures (up to 113°f). research has shown that high temperatures can damage and kill cancer cells, usually with minimal injury to normal tissues.  for many years, biologists have investigated cancer by using monolayer cell culture. it is bec...

Introduction: Prostate cancer (PCa) is the most prevalent malignant tumor in the male population worldwide and it is the second leading cause of cancer-related death in males. PCa is almost incurable due to the resistance of PCa to conventional treatments. Cancer stem cells (CSCs) theory suggests that a small subpopulation of cancer cells is responsible for tumor development, ...

abstract   background: the survival curves generally have been used for analysis of cell survival under stress conditions. they depict the relationship between the fraction of cells retaining their reproductive integrity and the absorbed dose. the median lethal dose, lethal concentration, 50% (lc 50 ) of a  toxin ,  radiation , or  pathogen  is the  dose required to kill half the members of a t...

In the framework of tube model, survival fraction dilated tube, φʹ(t), is essential since relaxation entire system described according to this quantity. However, a method define it in multi-chain simulations has yet be considered. study, primitive chain network were performed, and few structural quantities discussed as possible candidates for use φʹ(t). Before analysis, simulation was evaluated...

background & aim: esophageal cancer is one of the main common causes of death. the high prevalence of esophageal cancer in northern iran is an important public health problem. the main aim of this paper was to assess the factors affecting survival of  atients with esophageal cancer in neighbor provinces around the caspian sea using weibull mixture cure model and mixture cure model based on a no...