background: molecules expressed on the surface of infected erythrocytes (ie) with plasmodium falci-parum play important roles in malaria pathogenesis and immune evasion. some of these molecules are specific adhesive ligands mediating adhesion of ie to the vascular endothelium. in the current study, the antigens exposed on the surface of ie with different isolates and various binding subpopulati...

context occult hepatitis b (ohb), or persistent hbv dna in patients who are hepatitis b surface antigen (hbsag) negative, is a recently recognized entity. in an attempt to summarize the issues, this review presents an overview of the current proposed hypothesis on the clinical relevance and also updates the knowledge on the classification of ohb in different clinical settings. evidence acquisit...

introduction: as monoclonal antibodies are potential tools for characterization of soluble or cellular surface antigens, use of these proteins has always been considered in infertility and reproduction research. therefore, in this study, monoclonal antibodies against human sperm surface antigens were produced. material and methods: to produce specific clones against human sperm surface antigens...

introduction: intravenous drug users as a serious health problem in communities have economical and social effects as well as health and hygienic complications. viral infections may be transmitted through drug injection by shared syringes among users. the aim of this study has been to determine the relative frequency of hbv, hcv and hiv infection’s markers as epidemiological data in ahvaz. mate...

conclusions in hbeag positive chb patients, low serum hbsag level is a useful predictor of compensated cirrhosis. objectives the aim of our study was to evaluate serum hbsag level as a biomarker for compensated cirrhosis in hepatitis b e antigen (hbeag) positive chb patients. patients and methods two-hundred and one hbeag-positive chinese chb patients with or without cirrhosis were enrolled in ...

conclusions chaharmahal and bakhtiari province could be categorized as a low endemic region for hepatitis b infection, with a seroprevalence similar to that in other provinces of western iran. vaccination seems to influence its decrease, especially in adolescents and youth. more surveillance and attention to risk factors are suggested to identify high-risk groups and to implement vaccination. r...

hepatitis b virus (hbv) infection is the 10th leading cause of death worldwide. the most important diagnostic and screening marker for hbv infection is hepatitis b surface antigen (hbsag), and the most widely used hbsag screening test is enzyme-linked immunosorbent assay (elisa). in this study, an elisa assay has been developed for detection of hbsag using two novel monoclonal antibodies (mab) ...

background: application of adjuvants with microbial origins is a recently highlighted approach in the vaccinology trials. archaeosomes are among these microbial compounds with both adjuvant and liposomal activities and features. methods: in the present study, recombinant hbsag encapsulated into methanobrevibacter smithii (m. smithii) archaeosomes. balb/c mice immunized with this compound and hu...

background hepatitis b virus (hbv) is one of the most common chronic viral infections in the world. iran has a low to intermediate hbv prevalence and approximately 1.5 million people are living with hbv infection. the impact of hbv in iran is unknown and given the very low levels of alcohol consumption, this region provides an opportunity to examine the impact of isolated chronic hbv infection....