Using principles of completive and integrative self-sorting, a clean supramolecule-to-supramolecule transformation is realised that involves fusion of a 3-component rectangle and a 2-component equilateral triangle into a 5-component scalene triangle. While the spontaneous process takes 15 h at 25 °C, the catalytic transformation is completed within 1 h.

The geometries and binding energies of a recent buckyball tweezers (C(60)H(28)) and its supramolecular complexes are investigated using recently developed density functionals (M06-L and M06-2X) that include an accurate treatment of medium-range correlation energy. The pincer part of the tweezers, corannulene, has a strong attractive interaction with C(60). However, due to the entropy penalty, t...

Self-assembling peptides are capable of forming a complex containing a cavity where cytotoxic agents can be wrapped in a self-assembling manner. These complexes are beneficial for improving the pharmacological properties and pharmacokinetics of cytotoxic agents, such as doxorubicin and paclitaxel. In the present study, this self-assembling feature was successfully integrated into a hexapeptide ...

A photoresponsive single-handed double helical supramolecule composed of complementary strands bearing azobenzene moieties underwent a reversible trans-cis-isomerization regulated by photoirradiation, resulting in a change in its molecular length.

A bis-porphyrinic rectangle is created via a double self-assembly algorithm using two orthogonal coordination themes, i.e. first a 90 degrees building block composed of a dynamic heteroleptic Cu(I) or Ag(I) bisphenanthroline followed by a coordinative dimerization using the pyridine-zinc porphyrin motif; the spectroscopic and electrochemical properties as well as the dynamic nature of the supra...

The reaction of [Cp(Bn) Fe(η(5) -P5 )] (1) (Cp(Bn) =η(5) -C5 (CH2 Ph)5 ) with CuI selectively yields a novel spherical supramolecule (CH2 Cl2 )3.4 @[(Cp(Bn) FeP5 )12 {CuI}54 (MeCN)1.46 ] (2) showing a linkage of the scaffold atoms which is beyond the Fullerene topology. Its extended CuI framework reveals an outer diameter of 3.7 nm-a size that has not been reached before using five-fold symmetr...

Design, synthesis, and study of a synthetic barrel-stave supramolecule with p-octiphenyl "staves," beta-sheet "hoops," and hydrophobic exterior as well as internal carboxylate clusters are reported. Ion transport experiments indicate the formation of transmembrane pores at 5 < pH < 7 with nanomolar activity. Blockage of dye efflux from spherical bilayers by external Mg(OAc)(2) and internal 8-am...

The single crystals of tetrameric [Me3Sn(PhN2O2)]4 (1) supramolecule demethylates into single crystals of [Me2Sn(PhN2O2)2]2 dimer (2) and volatile Me4Sn, as a result of a crystal-to-crystal supramolecular structural transformation, which occurs upon heating and it is accompanied by a significant change of the molecular and crystal structures.