background: superoxide radicals are produced during oxidative metabolic processes, and removed by superoxide dismutase (sod) enzymes. controversial results have been reported regarding the tissue and plasma concentration of sod in patients with breast cancer. methods: venous blood was obtained from study participants and activity of sod enzyme was determined in 100 women. comparison was made be...

the human erythrocyte is a rich raw material for the purification of cu-zn superoxide dismutase (sod). we applied a simple and rapid procedure for the purification of sod from human erythrocytes by ion exchange chromatography. the purified sod had a specific activity of 2285.6 u/mg protein and gave a single band on polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate (sd...

iron is a pro-oxidant cofactor that may be linked to atherosclerosis progression. free iron catalyzes the generation of free radicals and free radicals promote the oxidation of lipids. reduction of body iron stores secondary to blood donation has been hypothesized to reduce lipid peroxidation. the aim of this study was to evaluate the association between blood donation and antioxidant enzymes a...

objective(s): to investigate the chronopharmacological effects of growth hormone on executive function and the oxidative stress response in rats. materials and methods: fifty male wistar rats (36-40 weeks old) had ad libitum access to water and food and were separated into four groups: diurnal control, nocturnal control, diurnal gh-treated, and nocturnal gh-treated animals. levels of cu, zn sup...

background: the purpose of this comparative study was to detect superoxide dismutase (sod) activities in fasciola hepatica, f. gigantica parasites, infected and healthy liver tissues in order to determine of species effects and liver infection on sods activity level. methods: fasciola spp. parasites and sheep liver tissues (healthy and infected liver tissues), 10 samples for each, were collecte...

osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. some studies show that osteoblasts can create inter-cellular free radicals that lead to cellular death. superoxide dismutase (sod) plays an essential role in cell defense against reactive oxygen metabolites. the purpose of this study was to measure the plasma sod activiti...

objective: ischemic preconditioning (ipc) is an endogenous phenomenon that can induce ischemic tolerance (it) in variety of organs such as brain. in this study, we examined the intermittent and prolonged normobaric hyperoxia (ho) on neurologic deficit scores, infarct volume, and superoxide dismutase activity. materials and methods: the rats were divided to four main groups. first two main grou...

conclusions our findings indicate that fullerenol nanoparticles decrease the brain infarction through enhancement of the sod activity during cerebral ischemia-reperfusion injury. results occlusion of mca induced considerable infarction and lesion in ischemic hemispheres of control ischemic rats (527 ± 59 mm3) in accompany with a decrease in the glutathione content (45%), and sod activity (29%) ...