purpose: to evaluate the effect of botulinum toxin-a (bta) injection into the inferior oblique (io) muscle in releaving the symptoms of superior oblique (so) palsy. methods: the study was conducted on patients who were referred for acquired so palsy with less than 2 years of duration. about 10-20 unit of bta was injected into the belly of the inferior oblique muscle through the inferotemporal q...

BACKGROUND AND PURPOSE Congenital superior oblique palsy is known to relate to trochlear nerve absence and a variable degree of superior oblique muscle hypoplasia. The purpose of this study was to determine whether superior oblique muscle volume predicts trochlear nerve absence in congenital superior oblique palsy. MATERIALS AND METHODS A retrospective study of high-resolution MR imaging to e...

BACKGROUND Congenital superior oblique palsy is usually associated with a structural abnormality of the superior oblique tendon. There have been many reports of familial congenital superior oblique palsy. However, there has been no MRI documentation of familial superior oblique hypoplasia. METHODS Ophthalmological examination and orbital MRI were performed in three patients in a pedigree with...

AIM To identify ARIX gene polymorphisms in patients with congenital superior oblique muscle palsy and to find the relation between the ARIX gene and congenital superior oblique muscle palsy. METHODS The three exons of the ARIX gene were sequenced by genomic DNA amplification with polymerase chain reaction (PCR) and direct sequencing in 15 patients with superior oblique muscle palsy (13 with c...

PURPOSE To search for a new definition of muscle hypoplasia in congenital or idiopathic superior oblique muscle palsy. DESIGN Retrospective case-control study. METHODS Cross-sectional areas of the superior oblique and 4 rectus muscles near the eye globe-optic nerve junction were measured by an image analysis software on magnetic resonance images of 50 patients with congenital or idiopathic ...

To identify ARIX gene and PHOX2B gene polymorphisms in patients with congenital superior oblique muscle palsy, 3 exons of the ARIX gene and PHOX2B gene were sequenced by genomic DNA amplification with polymerase chain reaction (PCR) and direct sequencing in 31 patients with congenital superior oblique muscle palsy and in 54 normal individuals. A family with a father and one daughter each having...

purpose: superior oblique palsy is a common cause of paralytic strabismus. this disorder causes diplopia, head posture and facial asymmetry. this retrospective study reviews patient with superior oblique (so) palsy operated at labbafinejad medical center from 1997 to 2007. methods: in this descriptive study, records of patients with so palsy scheduled for surgery were reviewed. forced duction t...

Vertical saccadic velocities in 10 patients who had unilateral superior oblique muscle palsy and 14 normal subjects were measured with the magnetic scleral search coil. The authors sought to determine whether downward saccades in patients who had superior oblique palsy are slow. Peak velocities of 10 degrees and 20 degrees saccades performed in the superior and inferior fields of the orbit, and...