in this paper the role of super paramagnetic iron oxide nanoparticles (spi) on platinum nanoclusters on activated carbon (pt/c) for electrocatalytic oxygen reduction reaction was considered. four composites of pt/c and super paramagnetic iron oxide nanoparticles were prepared with the same total composites weight and different loading of pt/c (1.2, 0.6, 0.4 and 0.3 mg ). the composite attached ...

conjugation of monoclonal antibodies to super paramagnetic nanoparticles is an effective method for cancer diagnosis and treatment. in this study the humanized anti her2/neu monoclonal antibody- herceptin- was conjugated to super paramagnetic iron oxide (spio) nanoparticles using edc method. the concentration of the conjugated antibodies was measured by bradford assay. the antibody-nanoparticle...

objective(s): this study describes the preparation, biodistribution of 153sm-dtpa-spion after intravenous injection in rats. materials and methods: the chelator dtpa dianhydride was conjugated to spion using a small modification of the well-known cyclic anhydride method. conjugation was done at a 1: 4 (spion: ccdtpa) molar ratio. conjugation reaction was purified with magnetic assorting column ...

the aim of this study was to develop a novel multifunctional nanoparticle, which encapsulates spion and gemcitabine in plga±peg to form multifunctional drug delivery system. for this aim, super paramagnetic iron oxide nanoparticles (spions) were synthesized and encapsulated simultaneously with gemcitabine (gem) in plga±peg copolymers via w/o/w double emulsification method. optimum size and enca...

Introduction: Iron plays an important role in physiological processes as a trace element. Today, iron oxide nanoparticles have attracted extensive attention due to their super paramagnetic properties and a variety of potential applications in many fields. The main objective of this study was to evaluate in vitro and in vivo toxic effects of the iron oxide nanoparticles on L929 cell line, kidney...

Abbreviations: BBB: Blood Brain Barrier; Ca: Calcium; CT: Computed Tomography; EM: Electro-Magnetic; EMA: European Medicines Agency; FDA: (U.S.) Food And Drug Administration; Fmri: Functional Magnetic Resonance Imaging; Gd: Gadolinium; GI: Gastro-Intestinal; IV: Intra-Venous; Mn: Manganese; MEMRI: Manganese-Enhanced MRI; Mn-DPDP: Chelated Manganese Nanoparticles; MRA: Magnetic Resonance Angiogr...

In this paper the role of super paramagnetic iron oxide nanoparticles (SPI) on Platinum nanoclusters on activated carbon (Pt/C) for electrocatalytic oxygen reduction reaction was considered. Four composites of Pt/C and super paramagnetic iron oxide nanoparticles were prepared with the same total composites weight and different loading of Pt/C (1.2, 0.6, 0.4 and 0.3 mg ). The composite attached ...

The aim of this study was to develop a novel multifunctional nanoparticle, which encapsulates SPION and Gemcitabine in PLGA±PEG to form multifunctional drug delivery system. For this aim, super paramagnetic iron oxide nanoparticles (SPIONs) were synthesized and encapsulated simultaneously with Gemcitabine (Gem) in PLGA±PEG copolymers via W/O/W double emulsification method. Optimum size and enca...

The aim of this study was to develop a novel multifunctional nanoparticle, which encapsulates SPION and Gemcitabine in PLGA±PEG to form multifunctional drug delivery system. For this aim, super paramagnetic iron oxide nanoparticles (SPIONs) were synthesized and encapsulated simultaneously with Gemcitabine (Gem) in PLGA±PEG copolymers via W/O/W double emulsification method. Optimum size and enca...

Abstract The aim of this study was to develop a novel multifunctional nanoparticle, which encapsulates SPION and Gemcitabine in PLGA±PEG to form multifunctional drug delivery system. For this aim, super paramagnetic iron oxide nanoparticles (SPIONs) were synthesized and encapsulated simultaneously with Gemcitabine (Gem) in PLGA±PEG copolymers via W/O/W double emulsification me...