Amlodipine besylate is a long‐acting calcium channel blocker used to treat chronic stable angina, vasospastic angina and hypertension. Amlodipine is a sparingly soluble orally administered drug and the rate of absorption is often controlled by the rate of dissolution. The rate of dissolution will increase by incorporating the drug in a fast dissolving dosage form. An attempt will be made to dev...

The objective of the study is to formulate mouth dissolving Tablet Moexipril with a variety super disintegrants and compare marketed disintegration tablet

the main objective of present research work is to formulate the clopidogrel fast dissolving tablets. clopidogrel, an antiplatelet drug, belongs to bcs class-ii and used to control heart attack, hypertension by inhibiting platelet activation and aggregation .the fast dissolving tablets of clopidogrel were prepared employing different concentrations of crospovidone and croscarmellose sodium in di...

Many patients especially children and elderly have difficulty in swallowing tablets and capsules and consequently unable to take medicine as prescribed. Almost 50% of the population is affected by such problem, resulting in the high incidence of non compliance and ineffective therapy. Most pharmaceutical forms for oral administration are formulated for direct ingestion, or for chewing, or for p...

ABSTRACT: The foremost intention of present research was the preparation and assessment mouth dissolving formulation Rivaroxaban its validation. During work, this tablet formulated by straight compression technique means Cros-carmellose sodium Sodium starch glycolate as super-disintegrants (concentration 2, 4, 6%) Avicel 102 a binder. preparations were exposed to different consideration paramet...

s: Mouth dissolving tablet is the fast growing and highly accepted drug delivery system. This study was aimed at development of Ketorolac Tromethamine mouth dissolving tablet, which can disintegrate or dissolve rapidly once placed in the oral cavity. Conventional Ketorolac tromethamine tablet require water to swallow it and have disadvantages like low disintegration rate, low solubility etc.Ket...

The polyherbal decoction, Gulugulutitakam is known for the treatment of various inflammatory conditions. For the ease of administration, this dosage form has been converted into tablets containing high amount of dry extract but it has the disadvantage of longer disintegration and dissolution parameters. In our attempt to develop tablets with improved disintegration and dissolution time, we have...

Objective: The rationale of the current work is to design, develop and optimize mouth dissolving tablet ambrisentan treat hypertension. Methods: Sodium starch glycolate crospovidone were used as super disintegrants in direct compression method create nine mouth-dissolving formulations. Wetting time, drug content, vitro disintegration dispersion dissolution time all assessed for produced Results...