BACKGROUND Clearing subglottic secretions has been proved to reduce ventilator-associated pneumonia. A manual method named the rapid flow expulsion maneuver was developed to clear subglottic secretions. This study evaluates its safety and effectiveness and analyzes the influential factors. METHODS This study was composed of 2 parts. In an in vitro study, secretions were instilled directly to ...

OBJECTIVE To study the effect of subglottic secretions drainage on the incidence of ventilator-associated pneumonia (VAP) in patients receiving mechanical ventilation. DESIGN A randomized clinical trial. SETTING A 12-bed general ICU. PATIENTS One hundred fifty patients with an expected duration of mechanical ventilation > 72 h were enrolled in the study. INTERVENTION Patients were rando...

abstract background: secretions contaminated with oral, nasal, and gastric bacteria accumulate in the subglottic space, above the endotracheal tube cuff. if these secretions are aspirated into lower airways, the intubated patient will be susceptible to ventilator‑associated pneumonia (vap). the aim of this study was to investigate the effect of inspiratory pause maneuver for intermittent subglo...

BACKGROUND AND PURPOSE Aspiration of secretions containing bacterial pathogens into the lower respiratory tract is the main cause of ventilator-associated pneumonia. Endotracheal tubes with subglottic secretion drainage can potentially reduce this and, therefore, the incidence of ventilator-associated pneumonia. New evidence on subglottic secretion drainage as a preventive measure for ventilato...

BACKGROUND Secretions contaminated with oral, nasal, and gastric bacteria accumulate in the subglottic space, above the endotracheal tube cuff. If these secretions are aspirated into lower airways, the intubated patient will be susceptible to ventilator-associated pneumonia (VAP). The aim of this study was to investigate the effect of inspiratory pause maneuver for intermittent subglottic secre...

Critically ill patients are intubated or tracheostomized because, in most cases, these individuals require invasive mechanical ventilation. The cannulae that are used include the cuff, which can act as a reservoir for oropharyngeal secretions, predisposing to ventilator-associated pneumonia. Studies have revealed that the suction of subglottic secretions through the dorsal suction lumen above t...

Pooling of contaminated secretions above the cuff of the endotracheal tube predisposes patients to ventilator-associated pneumonia (VAP). Subglottic secretion drainage requires a special endotracheal tube that has a separate lumen that opens in the subglottic region above the tracheal tube. A recent meta-analysis of the 5 randomized clinical trials that evaluated the efficacy of removing these ...

Introduction The major cause of ventilator-associated pneumonia (VAP) is the aspiration of bacteria-laden subglottic secretions past the cuff of the endotracheal tube (ETT) [1]. When the ETT cuff is inflated to the correct wall pressure, excess cuff material folds and causes involutions thereby forming channels, which allow leakage of subglottic secretions to the lungs [2]. Now, new ETT cuffs h...

BACKGROUND Continuous aspiration of subglottic secretions is effective in preventing ventilator-associated pneumonia, but it involves a risk of mucosal damage. The main objective of our study was to determine the incidence of airway complications related to continuous aspiration of subglottic secretions. METHODS In consecutive adult patients with continuous aspiration of subglottic secretions...

RATIONALE Ventilator-associated pneumonia (VAP) causes substantial morbidity and mortality. The influence of subglottic secretion drainage (SSD) in preventing VAP remains controversial. OBJECTIVES To determine whether SSD reduces the overall incidence of microbiologically confirmed VAP. METHODS Randomized controlled clinical trial conducted at four French centers. A total of 333 adult patie...