purpose: the first step to manage motor impairment of upper limb in patients with subacute stroke is having an accurate assessment tool. the fugl-meyer assessment of upper extremity and 9-hole pegboard test are used to evaluate motor function and hand dexterity in stroke survivals. the present study aimed to investigate the test-retest reliability and minimal detectable change (mdc) in these tw...

Purpose: The first step to manage motor impairment of upper limb in patients with subacute stroke is having an accurate assessment tool. The Fugl-Meyer assessment of upper extremity and 9-hole pegboard test are used to evaluate motor function and hand dexterity in stroke survivals. The present study aimed to investigate the test-retest reliability and minimal detectable change (MDC) in these tw...

BACKGROUND . Somatosensory input to the motor cortex may play a critical role in motor relearning after hemiparetic stroke. OBJECTIVE . The authors tested the hypothesis that motor recovery after hemiparetic stroke relates to changes in responsiveness of the sensorimotor cortex (SMC) to somatosensory input. METHODS . A total of 10 hemiparetic stroke patients underwent serial functional magn...

objectives: stroke is the leading cause of long-term disability. hand motor impairment resulting from chronic stroke may have extensive physical, psychological, financial, and social implications despite available rehabilitative treatments. the best time to start treatment for stroke, is in sub-acute period. repetitive transcranial magnetic stimulation (rtms) is a method of stimulating and augme...

BACKGROUND Poststroke depression (PSD) is a common form of stroke patients. Whether the risk of PSD is influenced by the stroke lesion location and sex remains a matter of debate. The objective of this study was to examine the association between the risk of PSD and the stroke lesion location and sex by performing a systematic meta-analysis. METHODS Subgroup analyses were performed according ...

BACKGROUND AND PURPOSE In vivo changes in tissue pH and energy metabolism are key to understanding stroke pathophysiology. Our goal was to study pH changes in subacute ischemic stroke and their relation to energy metabolism, which, unlike acidosis in acute stroke, are not yet well understood. METHODS We measured tissue pH and phospholipid as well as cell energy markers, including creatine, ph...

BACKGROUND AND PURPOSE Before Phase III trials of acute stroke therapies, proof-of-concept MRI trials are increasingly used to gauge the likelihood of success. Given that animal models use infarct volume as the end point, Phase II trials have aimed to translate the findings using infarct growth. These trials could be expedited if subacute diffusion-weighted imaging lesion volume replaced late T...

BACKGROUND AND PURPOSE Acute ischemic stroke patients who receive recombinant tissue plasminogen activator (rt-PA) within 3 hours of symptom onset are 30% more likely to have minimal to no disability at 3 months. During hospitalization, short-term disability is subjectively measured by discharge disposition, whether to home, inpatient rehabilitation, a skilled nursing facility, or subacute care...