E-mail: [email protected] The experiment was performed on white rats and content of malondialdehyde and conjugated dienes in the retina and blood plasma in the condition of streptozotocineinduced diabetes development and quercetine and lipoate application was studied. In such conditions, the use of drugs studied significantly prevented an increase in temporary products of lipid peroxidation ...

BACKGROUND Metastatic insulinoma is a disease associated with a poor life expectancy. CASE REPORT The case of a presently 68 year old female with malignant, metastatic insulinoma is reported. Due to severe clinical symptoms surgical tumor mass reduction was conducted. Furthermore the patient underwent a chemotherapy using streptozotocine and fluorouracil. After two years without any symptoms,...

The present study aims to examine the anti-diabetic effects of fullerene C60 nanoparticle, as an anti-oxidant compound, on serum glucose level, body weight, food and water intake, pancreatic oxidative stress in rats with type 1 diabetes. Diabetes mellitus was induced by single intravenous injection streptozotocine (45 mg/kg) into tail vein rats. Four groups were divided follow: normal, normal t...

triazine derivatives are small synthetic peptides with no apparent toxicity and high target specificity in central nervous system. hippocampal tissue is the most vulnerable area in the alzheimer’s disease (ad). the aim of this study was to investigate the neuroprotective effect of triazine in ad induced by intra-cerebro-ventricular (i.c.v.) administration of streptozotocine (stz). male wistar, ...

the search for indigenous natural antidiabetic agents is still ongoing. securigera securidaca seeds are reputed in folk medicine for their value as an antidiabetic remedy, so the present study was carried out to investigate the hypoglycemic efficacy in both normal and streptozotocine (stz)-induced diabetic rats. hydroalcoholic extract of the seeds were administered orally with doses of 200, 400...

The influence of solvent polarity for hydroethanol (a), chloroform (b), and carbon tetrachloride (c) on bioactive extraction contents Portulaca oleracea (II) Achillea eriophora DC (III) were evaluated by GC-MS analysis. antidiabetic antilipidemic properties different extracts investigated streptozotocine-induced diabetic rats compared to glibenclamide as well-known chemical drug the treatment d...

AMAÇ: Sunulan bu çalışmada yüksek yağlı diyet ve streptozotosin ile deneysel tip 2 diyabet oluşturulan farelerde metformin tedavisinin karaciğer böbrek dokularında antioksidan etkisinin araştırılması amaçlandı.GEREÇ VE YÖNTEM: Yirmi bir adet yetişkin (11-12 haftalık 15-18 g) C57BL6 erkek fare rastgele üç gruba ayrıldı; Kontrol grubu (K), Diyabet (D), Diyabet+Metformin tedavi (D+MTF). D D+MTF gr...