Hansen, T. V. A., Fryganas, C., Acevedo, N., Carballo, L. R., Thamsborg, S. M., Mueller-Harvey, I. and Williams, A. R. (2016) Proanthocyanidins inhibit Ascaris suum glutathione-Stransferase activity and increase susceptibility of larvae to levamisole and ivermectin in vitro. Parasitology International, 65 (4). pp. 336-339. ISSN 1873-0329 doi: 10.1016/j.parint.2016.04.001 Available at http://cen...

Age-associated changes in several antioxidative factors were studied in blood and liver from mice prone to accelerated senescence aged O.7 to 1.4 years and mice resistant to acce]erated senescence aged 1.0 to 2.1 years. In both strains, actiyities of hepatic glutathione peroxidase (GSH-Px) and glutathione-Stransferase (GST) decrefised significantly with age, and the actiyity of superoxide dismu...

Organosulfur compounds (OSCs) present in garlic and onion oil have been shown to inhibit chemical carcinogenesis. In this study, we compared the chemopreventive efficacy of five lipidand four water-soluble OSCs using the murine nuclear aberration assay. Administration of diallyl sulfide and 5-allyl cysteine p.o. at a dose of 200 mg/kg 3 h prior to i.p. 1,2-dimethylhydrazine (DMII) injection (20...

introduction: the fate of xenobiotics that is present, increasing day by day. the increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. methods: the present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by panax ginseng ...

resistance of the weanling rat to acetaminophen (ap ap)-induced hepatotoxicity is manifested with regard to a surge in apap-glutathione (osh) conjugate formation in the liver [allameh et al. mech aging dev 95(1997)71]. the present study was conducted to assess the role of this detoxification pathway in apapinduced lipid per6xidationin the liver. lipid peroxidation measured as thiobarbituric aci...

Fipronil toxicity and metabolism were studied in two insecticide-resistant, and one susceptible western corn rootworm (Diabrotica virgifera virgifera, LeConte) populations. Toxicity was evaluated by exposure to surface residues and by topical application. Surface residue bioassays indicated no differences in ®pronil susceptibility among the three populations. Topical bioassays were used to stud...

The effect of bromocriptine, a dopamine agonist, administered in the form of bromocriptine alginate nanocomposite (BANC) was studied on Parkinson’s disease (PD) model flies. The synthesized BANCwas subject to characterization and, at a final concentration of 0.5, 1.0 and 1.5 μM, was mixed in diet. The PD flies were allowed to feed on it for 24 days. A significant dose-dependent delay in the los...

D. Stuber and K. Henco. 1994. 6xHis-NiNTA chromatography as a superior technique in recombinant protein expression/purification. Methods Mol. Biol. 31:371-387. 3.Galibert, F., E. Mandart, F. Fitoussi, P. Tiollais and P. Charnay. 1979. Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli. Nature 281:646-650. 4.Gentz, R., C.-H. Chen and C.A. Rosen. 1989. Bioassay fo...