Journal:
:iranian red crescent medical journal
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malihea khaleghian department of medical genetics, cancer institute of iran, tehran university of medical sciences, tehran, ir iran
issa jahanzad department of pathology, immunohistochemistry laboratory, cancer institute of iran, tehran university of medical sciences, tehran, ir iran
abbas shakoori department of medical genetics, cancer institute of iran, tehran university of medical sciences, tehran, ir iran
amirnader emami razavi department of pathology, iran national tumor bank, cancer institute of iran, tehran university of medical sciences, tehran, ir iran
cyrus azimi department of medical genetics, cancer institute of iran, tehran university of medical sciences, tehran, ir iran; corresponding author: cyrus azimi, department of medical genetics, cancer institute of iran, tehran university of medical sciences, p. o. box: 1419733141, tehran, ir iran. tel/fax: +98-2166945120, e-mail:
background the incidence rate of gastric cancer in western countries has shown a remarkable decline in the recent years while it is still the most common cancer among males in iran. the proto-oncogene myc, located at 8q24.1, regulates almost 15% of human genes and is activated in 20% of all tumors. the amplification of myc and overexpression of its protein product are observed in 15 - 30% of ga...