introduction: the human skin is an active medium from the optical point of view. therefore, the diagnostic and therapeutic techniques employing light are increasing. current optical techniques are based on the measurement of the intensity of reflected absorbed or backscattered light from or within skin. studies have shown that biological tissues, and in particular skin, demonstrate polarization...

The successful genetic engineering of patient T cells with γ-retroviral vectors expressing chimeric antigen receptors or T-cell receptors for phase II clinical trials and beyond requires the large-scale manufacture of high-titer vector stocks. The production of retroviral vectors from stable packaging cell lines using roller bottles or 10- to 40-layer cell factories is limited by a narrow harve...

We used the Support Vector Machines in a classification approach to 'beat the market'. Given the fundamental accounting and price information of stocks trading on the Australian Stock Exchange, we attempt to use SVM to identify stocks that are likely to outperform the market by having exceptional returns. The equally weighted portfolio formed by the stocks selected by SVM has a total return of ...

Abstract Markov manpower planning models have extensively been analyzed in the past in order to find an optimal personnel strategy for which the manpower system evolves towards desirable stocks. So far, those models do not take into account interactions among different organizational decision levels. In this paper, a multi-level manpower planning model is presented that considers, besides the d...

In this study, we report the characterization of seven trypanosome stocks isolated in different geographical areas of Latin America and from different vector species, by analysis of kinetoplast DNA (kDNA) restriction fragmentlength polymorphism, using five different restriction endonucleases, and genomic DNA by duplex PCR assay. According to the statistical study, the stocks were grouped into t...

Previous studies (1982,1987) have emphasized the superiority of sylvatic vector species over domestic species as xenodiagnostic agents in testing hosts with acute or chronic infections by T. cruzi "Y" stock. The present study, which is unique in that it contains data on both infectivity rates produced by the same stock in 11 different vector species and also the reaction of the same vector spec...

BACKGROUND During the past twelve years, lentiviral (LV) vectors have emerged as valuable tools for transgene delivery because of their ability to transduce nondividing cells and their capacity to sustain long-term transgene expression in target cells in vitro and in vivo. However, despite significant progress, the production and concentration of high-titer, high-quality LV vector stocks is sti...