نتایج جستجو برای: stimulating factor

تعداد نتایج: 879771  

Journal: :molecular biology research communications 2014
mohsen esmaili durdi qujeq ali asghar yoonesi farideh feizi mohammad ranaee

the present study aimed at investigating the beneficial effects of co-administering granulocyte colony–stimulating factor (g-csf) and stem cell factor (scf) in a model of chronic liver injury induced by thioacetamide (taa). biochemical and histopathology- cal examinations were performed on serum and liver specimens. at the end of the treatment period, the rats were anesthetized with ether, seru...

Journal: :basic and clinical neuroscience 0
mohsen marzban mehrdad bakhtiary mehdi mehdizadeh mohamad taghi joghataei samideh khoei vahid pirhajati mahabadi

introduction: this study was designed to investigate the effects of granulocyte colony-stimulating factor (g-csf) administration in rats for 6 weeks after traumatic brain injury (tbi). methods: adult male wistar rats (n = 30) were injured with controlled cortical impact device and divided into four groups. the treatment groups (n = 10 each) were injected subcutaneously with recombinant human g-...

Journal: :research in molecular medicine 0
ali asghar yoonesi durdi qujeq mohsen esmaili farideh feizi

background: there are many reports regarding to effects of granulocyte colony-stimulating factor (g-csf) and stem cell factor (scf)alone in liver repair .but conflicting data have been reported regarding the role of growth factors such as g-csf and scf in the liver regeneration system. also, there is not such data regarding to effects of co-administration both of g-csf and scf in the liver dama...

Journal: :international journal of reproductive biomedicine 0
behnaz sheikholslami mojdeh salehnia mojtaba rezazadeh

the cytokine of granulocyte macrophage colony stimulating factor (gm-csf) is a glycoprotein, which is synthesized in the female reproductive tract and has embryonic trophic effect in mammals. the objective of this study was to examine the optimal dosage of gm-csf to improve the mouse embryo development in vitro. to collect two and eight cells embryos, the pregnant nmri mice were sacrificed by c...

Journal: :iranian biomedical journal 0
لعیا قهاری laya ghahari منوچهر صفری manouchehr safari محمدتقی جغتایی mohamad taghi joghataei مهدی مهدی زاده mehdi mehdizadeh منصوره سلیمانی mansoureh soleimani

background: stroke is the third leading cause of death. hypothermia has been recognized as an effective method in reducing brain injury. in this study, we assessed the effects of granulocyte colony-stimulating factor (g-csf) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in wistar rats. methods: forty male rats were used in fiv...

Journal: :مجله علوم اعصاب شفای خاتم 0
ali mehri a. student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran b. neuroscience department, mashhad university of medical sciences, mashhad, iran mohammad moein vakilzadeh a. student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran b. neuroscience department, mashhad university of medical sciences, mashhad, iran amirhossein heidari a. student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, iran b. neuroscience department, mashhad university of medical sciences, mashhad, iran

traumatic brain injury (tbi) is described as a situation in which the brain is damaged by an external force. it is considered to be a chief problem in health care. pharmacotherapy and stem cell therapy are the main treatments used in tbi. the purpose of these procedures is to control the inflammation in injured regions of brain. currently, there is no effective care for tbi that could regenerat...

Journal: :iranian journal of biotechnology 2008
hamed naghoosi farida behzadian alireza saeedinia seyed ali ghorashi

human granulocyte colony stimulating factor (hg-csf) induces proliferation and differentiation of granulocyte progenitor cells. this glycoprotein is currently being used for treatment of neutropenia, in patients who have undergone bone marrow transplantation. so far, different researchers have tried to enhance hg-csf biological activity and stability. in this study, polymerase chain reaction (p...

A RABBANI, B GOLIAEI,

The role of alveolar macrophages in the production of granulocyte/ macrophage colony-stimulating factor(s) by the rat lung was investigated. Lavaged lungs, when incubated at proper weight per volume of culture medium, produced the same amount of colony-stimulating factor as unlavaged ones. Both lavaged and unlavaged lungs produced similar types of colony-stimulating factor (s). Prolonged i...

Journal: :iranian biomedical journal 0
ولی الله بابایی پور valiollah babaeipour سیروان خوانچه زر sirwan khanchezar محمدرضا مفید mohammad reza mofid مهدی پسران حاجی عباس mahdi pesaran hagi abbas

background: the protein hormone granulocyte colony-stimulating factor (gcsf) stimulates the production of white blood cells and plays an important role in medical treatment of cancer patients. methods: an efficient process was developed for heterologous expression of human gcsf in e. coli bl21 (de3). the feeding rate was adjusted to achieve the maximum attainable specific growth rate under crit...

Journal: :international journal of hematology-oncology and stem cell research 0
sarah mousavi department of clinical pharmacy and pharmacy practice, faculty of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran mina dadpoor pharm d student, faculty of pharmacy and pharmaceutical sciences, isfahan university of medical sciences, isfahan, iran farzaneh ashrafi hematology and medical oncology department, school of medicine, isfahan university of medical sciences, isfahan, iran acquired immunodeficiency research center, isfahan university of medical sciences, isfahan, iran

background: granulocyte colony stimulating factors (gcsf) are high cost agents commonly recommended for primary and secondary prophylaxis of chemotherapy-induced neutropenia and febrile neutropenia. gcsfs have been shown to be beneficial in some patient subgroups, although they are probably overused in clinical settings. the american society of clinical oncology (asco) guidelines summarize curr...

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