OBJECTIVE To compare the effectiveness and safety of the methylphenidate produced in Iran (Stimdate®) with its original brand (Ritalin®) in children with Attention deficit hyperactivity disorder (ADHD). METHODS In this double-blinded randomized clinical trial, 30 patients with ADHD who were 6 to 16 years old, were divided into two groups: 15 in Stimdate® and 15 in Ritalin® group. The two grou...

ôbjective: to compare the effectiveness and safety of the methylphenidate produced in ïran (stimdate®) with its original brand (ritalin®) in children with âttention deficit hyperactivity disorder (âdhd). methods: ïn this double-blinded randomized clinical trial, 30 patients with âdhd who were 6 to 16 years old, were divided into two groups: 15 in stimdate® and 15 in ritalin® group. the two grou...

objectives: the aim of this randomized clinical trial was to assess the efficacy of stimdate compared to ritalin in the treatment of children with attention deficit hyperactivity disorder (adhd). method: sixty four subjects (45 boys and 15 girls) aged 5-13 who were diagnosed with adhd based on (dsm-iv-tr) criteria were selected for this study. the subjects were randomly assigned to two groups: ...

Co(II), which induces the assembly of tubulin in the absence of associated proteins, binds to multiple sites on the protein in a low ionic strength medium. However, in the presence of concentrations of buffer and GTP used in assembly reactions, the number of sites occupied by Co(I1) is drastically reduced. At GTP and Co(I1) concentrations where the major polymerized products are broad sheets of...