BACKGROUND Protective effect of early pregnancy and short-term estrogen treatment (STET), against breast cancer is well established. The underlying mechanisms are not well understood. In this study, we compared the mammary gland cellular microenvironment influenced/induced by parity and STET alongside age-matched controls. METHODS Parous, STET, and control rats were injected with N-methyl-N-n...

Germ cells normally differentiate in the context of encapsulating somatic cells. However, the mechanisms that set up the special relationship between germ cells and somatic support cells and the signals that mediate the crucial communications between the two cell types are poorly understood. We show that interactions between germ cells and somatic support cells in Drosophila depend on wild-type...

The knowledge of three-dimensional structures at atomic resolution of membrane transport proteins has improved considerably our understanding of their physiological roles and pathological implications. However, most structural biology techniques require an optimal candidate within a protein family for structural determination with (a) reasonable production in heterologous hosts and (b) good sta...

This paper examines the viability of security transaction excise taxes (STETs) as one policy tool for promoting a more stable financial environment, specifically with respect to the U.S. economy. Contrary to a large recent critical literature, we show that a STET can be designed without creating large distortions between segments of the financial market. We also show that a modest STET for the ...

‘STET model’ is a framework for realistic surveillance setup in which multi-target multi-sensor scenario can be modeled for surveillance applications. The components of STET model framework are Sensor (S), Targets (T), Environment (E) and Terrain (T). The set of characters relevant to surveillance operation of the sensor is captured in Sensor modeling. In target modeling, the characteristics of...

CSELT is the STET Group's Company for the study, research, experimentation and qualification for telecommunications and information technology. It contributes to the study of advanced systemistic scenarios, plays a link role between academic and applied research and has a strong presence in the international context, through the participation in common research programs and standardization acti...