Subcutaneous fat atrophy at the site of multiple injections can follow intradermal or intramuscular administration of steroids to treat inflammatory diseases. This condition takes several months to develop, and usually patients seek medical attention due to cosmetic deformities. Several methods, including fat transfer, filler injection and normal saline injection haven been proposed to tr...

The intersegmental muscles of the giant silkmoth Antheraea polyphemus (Cramer) can undergo two forms of degenerative changes: a wasting atrophy that lasts about 6 days or rapid dissolution that is completed within 30 h. Muscle atrophy is induced by a dramatic decline in the endogenous titres of the steroid moulting hormone 20-hydroxyecdysone. 20-Hydroxyecdysone appears to act as a trophic facto...

Thirty-two patients with systemic lupus erythematosus were evaluated clinically and with computed tomography in order to determine whether the occurrence of cerebral atrophy in systemic lupus erythematosus was due to the steroid therapy or the cerebral manifestations of the disease itself. Of these patients, 14 had central nervous system manifestations of the disease (lupus cerebritis) and 12 o...

conclusions the individuals should have multidisciplinary approach for the variety of disorders to maintain the appropriate treatment for a better appearance of the patients. case presentation we describe a patient with progressive hemifacial atrophy at right facial side who developed granulomatous uveitis and periferic retinal vasculitis in his left eye. we started topical and systemic steroid...

BACKGROUND Injections of corticosteroids are commonly used for a variety a dermatologic conditions but may cause local, persistent cutaneous atrophy, with few therapeutic options. OBJECTIVE To determine the effectiveness of bacteriostatic normal saline infiltration on the improvement of corticosteroid-induced cutaneous atrophy. MATERIALS AND METHODS Four patients with corticosteroid-induced...

Background: Systemic corticosteroid injections are used to treat a variety of medical conditions. Inaccurate placement of intramuscular injections of corticosteroid can result in local lipoatrophy, and a resultant cosmetic deformity. Objective: Describe the condition, and a simple, reproducible method of correcting the volume deficiency and skin changes associated with steroid induced lipoatrop...

Melasma is a cosmetic disorder with profound psychological impact. Multiple therapies are available for melasma but no therapy the gold standard. The most of patients suffer from relapses and recurrences which force patient to opt over-the-counter medications containing topical steroids or indigenous medications. Use these has led emergence complicated cases refractory treatment. Along hyperpig...