background: staphylococcus aureus, the major virulence factor of hospital and community acquired infections, secretes numerous exotoxins (super antigens), which may affect immunological and inflammatory status in psoriatic skin lesion. objectives: this study is designed to compare the s. aureus super antigens level in sera of psoriatic patients with normal cases (nevus). patients and methods: a...

conclusions based on the findings of this study, s. aureus enterotoxin c (sec) has been detected in synovial fluid of patients with rheumatoid arthritis by pcr and elisa methods. these valuable findings may describe the exact etiology of the ra and as well as change the methods of its diagnosis and treatment. this is the first research, which has shown the staphylococcal entc gene in synovial f...

BACKGROUND About 20 different types of staphylococcal enterotoxins are produced by Staphylococcus aureus, in which type A is more common in food poisoning syndrome. Also staphylococcal enterotoxin A superantigen is a potent inducer of cytotoxic T lymphocyte activity and cytokine production and could stimulate T cells containing T-cell receptor beta chain domains when binding to major histocompa...

background rheumatoid arthritis (ra) is the most common chronic inflammatory disease. the staphylococcal superantigens are considered as the causative agent of ra disease. objectives this study aimed to assess the presence of staphylococcal enterotoxin d in synovial fluid and blood of patients with ra. patients and methods a total of 120 blood and sf samples of patients with ra were studied. ba...

A sensitive and specific monoclonal antibody-based sandwich enzyme-linked immunosorbent assay (ELISA) was established and validated for the detection of staphylococcal enterotoxin A (SEA). After routine fusion and selection, 10 monoclonal antibodies showed high affinity for SEA. An optimal pair for sandwich ELISA was selected by pairwise interaction analysis. After optimization, the limit of de...

BACKGROUND: Staphylococcal foodborne intoxication is the most common cause of foodborne illnesses by Staphylococcus aureus strains and most are caused by the enterotoxins of S. aureus. Staphylococcal enterotoxin A (SEA) is the most frequently responsible for staphylococcal food poisoning outbreaks. From a food safety and human health point of view, lactic acid bacteria (LAB) may provide a promi...

background accurate and rapid diagnosis of bacterial arthritis is not always possible in unvaccinated (streptococcus pneumoniae and haemophilus influenzae type b) children in iran. objectives searching the staphylococcal superantigen (entrotoxin a, b, c and tsst1) in synovial fluid of cases with inflammatory arthritis. patients and methods this cross sectional study was implemented in the pedia...

Staphylococcal enterotoxin A is well known as a superantigen and able to be used for cancer immunotherapy. In this study, recombinant Staphylococcal enterotoxin A was genetically conjugated to epidermal growth factor to produce a chimeric protein recombinant Staphylococcal enterotoxin A-epidermal growth factor expressed in Escherichia coli. The recombinant Staphylococcal enterotoxin A-epidermal...