objective(s): considering the fact that the standardized uptake value (suv) of a normal lung tissue is expressed as x±sd, x+3×sd could be considered as the threshold value to outline the internal tumor volume (itv) of a lung neoplasm. methods: three hollow models were filled with 55.0 kbq/ml fluorine18- fluorodeoxyglucose (18f-fdg) to represent tumors. the models were fixed to a barrel filled w...

BACKGROUND This study is an assessment of the impact of acquisition times on SUV with [(18)F]FDG-PET/CT on healthy livers (reference organ with stable uptake over time) and on tumors. METHODS One hundred six [(18)F]FDG-PET/CT were acquired in list mode over a single-bed position (livers (n = 48) or on tumors (n = 58)). Six independent datasets of different durations were reconstructed (from 1...

PURPOSE To compare the conspicuity of malignant lesions between FDG PET/CT and a new simultaneous, time-of-flight (TOF) enabled PET/MRI scanner. METHODS All patients underwent a single-injection of FDG, followed by a dual imaging protocol consisting of PET/CT followed by TOF PET/MRI. PET/CT and PET/MRI images were evaluated by two readers independently for areas of FDG uptake compatible with ...

objective(s): the present study was conducted to examine whether the standardized uptake value (suv) may be affected by the spatial position of a lesion in the radial direction on positron emission tomography (pet) images, obtained via two methods based on time-of-flight (tof) reconstruction and point spread function (psf). methods: a cylinder phantom with the sphere (30mm diameter), located in...

UNLABELLED 18F-FDG PET is increasingly being used to monitor the early response of malignant tumors to chemotherapy. Understanding the reproducibility of standardized uptake values (SUVs) is an important prerequisite in estimating what constitutes a significant change. METHODS Twenty-six patients were studied on 2 separate occasions (mean interval +/- SD, 3 +/- 2 d; range, 1-5 d). A static PE...

AIM To study the influence of dual time point 18F-FDG PET/CT in textural features and SUV-based variables and their relation among them. METHODS Fifty-six patients with locally advanced breast cancer (LABC) were prospectively included. All of them underwent a standard 18F-FDG PET/CT (PET-1) and a delayed acquisition (PET-2). After segmentation, SUV variables (SUVmax, SUVmean, and SUVpeak), me...

Backgrounds and Purpose—In indolent non-Hodgkin lymphoma, histological transformation is a dramatic event which reduces the prognosis significantly. SUVmax values from FDG-PET/CT help differentiate between aggressive and indolent lymphomas, and transformed indolent lymphomas also show an increased FDG uptake. Possibly FDG uptake increases early in the clinical course and could predict histologi...

The aim of this study was to investigate thalamic and basal ganglia (BG) metabolism in temporal lobe epilepsy (TLE) on interictal 18F-FDG PET using standardized uptake value (SUV). Retrospective review of data was undertaken for patients who were surgically treated for medically intractable TLE. All patients underwent 18F-FDG PET, MRI brain and EEG as preoperative workup, and subsequently under...

Standardized uptake values (SUVs) are the most widely used quantitative imaging biomarkers in PET. It is important to evaluate the variability and repeatability of measured SUVs. Phantom studies seem to be essential for this purpose; however, repetitive phantom scanning is not recommended due to the decay of radioactivity. In this study, we performed count-based image reconstruction to avoid th...